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UnknownQuantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia.
Not available
S-EPMC3397783 | biostudies-literature
TranscriptomicsImpact of RNA isolation methods for RNA-seq on gene expression. Here RNA was isolated from HEK293T cells using either Columns, magnetic beads with/without proteinase K or magnetic beads without proteinase K but heating. RNA was processed using prime-seq.
Here silica column and bead based RNA isolation was performed. The two methods were compared using prime-seq to determine the effect of the RNA isolation method on gene expression quantification. This was tested for three different types of input samples, PBMCs, HEK293T cells and striatal mouse tis...
ORGANISM(S): Homo sapiens 
2021-08-01 | E-MTAB-10142 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology
The host immune response plays a critical role not only in protection from human leishmaniasis, but also in promoting disease severity. Although candidate gene approaches in mouse models of leishmaniasis have been extremely informative, a global understanding of the immune pathways active in lesions...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-GEOD-55664 | biostudies-arrayexpress
TranscriptomicsCD8 T cells induce perforin-dependent pathology in Leishmania braziliensis infection
The mechanisms that mediate immunopathologic responses in infectious diseases are often less well understood than how the pathogens are controlled. Here, we have investigated what causes increased pathology following infection with the protozoan parasite, Leishmania braziliensis. We focused on CD8...
ORGANISM(S): Homo sapiens 
2013-07-08 | E-GEOD-43880 | biostudies-arrayexpress
UnknownA conserved chronobiological complex times C. elegans development
Not available
S-SCDT-10_1038-S44318-025-00585-Z | biostudies-other
ProteomicsThe B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM
This data set contains the mass spectrometry raw files for the paper The B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM. In multiple sclerosis (MS) intrathecal B lymphocytes are directly involved in inflammation and secrete oligoclonal immunoglobulin. Ho...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-11 | MSV000086842 | MassIVE
Transcriptomicscis-Expression QTL Analysis of Established Risk Variants for Colorectal Cancer
Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions ...
ORGANISM(S): Homo sapiens 
2012-01-31 | E-GEOD-31737 | biostudies-arrayexpress
UnknownPredicting 90-day survival of patients with COVID-19: Survival of Severely Ill COVID (SOSIC) scores.
Not available
S-EPMC8665857 | biostudies-literature
UnknownImpairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Not available
S-EPMC9664128 | biostudies-literature
UnknownCytokine Storms in COVID-19, Hemophagocytic Lymphohistiocytosis, and CAR-T Therapy.
Not available
S-EPMC11976493 | biostudies-literature
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