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TranscriptomicsA molecular and phenotypic integrative approach to identify a no effect dose level for anti-androgen induced testicular toxicity
With the advent of high information content technologies, especially microarrays, it is pertinent to determine the impact of molecular data on the NOAELs. Consequently, we conducted an integrative study to identify a no transcriptomic effect dose using microarray analyses coupled with qPCR and deter...
ORGANISM(S): Rattus norvegicus 
2011-03-29 | E-GEOD-28202 | biostudies-arrayexpress
UnknownLarge-scale analysis of Drosophila core promoter function using synthetic promoters.
Not available
S-EPMC8842121 | biostudies-literature
TranscriptomicsNew insights into the molecular mechanisms of 1,3-dinitrobenzene-induced testicular toxicity
Several studies have shown that 1,3-dinitrobenzene (DNB) causes injury to Sertoli cells and induces apoptosis in the surrounding germinal cells in male laboratory rats ; however, the mechanisms by which DNB functions are not well understood. In this context, we have conducted studies using standard ...
ORGANISM(S): Rattus norvegicus 
2012-07-13 | E-GEOD-39344 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of non-genotoxic hepatocarcinogens and hepatotoxicants in rat liver
Liver tumors in rodents are frequently induced by non-genotoxic carcinogens. These hepatocarcinogens generally activate hepatic nuclear receptors (e.g., CAR and PXR), resulting in a cascade of signals causing modifications in the expression of genes responsible for several processes involved in carc...
ORGANISM(S): Rattus norvegicus 
2013-07-31 | E-GEOD-39350 | biostudies-arrayexpress
UnknownSpatially resolved qualified sewage spot sampling to track SARS-CoV-2 dynamics in Munich - One year of experience.
Not available
S-EPMC8294104 | biostudies-literature
ProteomicsMass spectrometry-based draft of the mouse proteome
Quantitative draft map of the proteomes of 41 healthy tissues of the animal model Mus musculus and a panel of 66 murine pancreatic ductal adenocarcinoma cell lines and. Our in-depth analysis provides evidence for proteins encoded by >16,000 genes (~76% of the total annotated protein-coding genes), w...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-07-09 | MSV000089856 | MassIVE
UnknownKRAS signaling in malignant pleural mesothelioma
Not available
S-SCDT-EMM-2020-13631 | biostudies-other
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