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Despite the advancements in screening and treatment, the incidence of breast cancer (BC) and associated mortalityare projected to increase. Therefore, developing a companion diagnostic for BC remains important. To explore the urinary proteome for potential biomarkers for BC.  A total of 130 partic...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD061502 | Pride
This study presents a cell-type–resolved quantitative proteomics analysis of paired primary and recurrent ascites samples from patients with high-grade serous ovarian carcinoma (HGSOC). Ascites samples were collected from three patients (IROC60, IROC65, and IROC126) at diagnosis and upon disease rec...
ORGANISM(S): Homo sapiens (Human) 
2026-08-18 | PXD073562 | Pride
Mis-sense mutations affecting TP53 promote carcinogenesis both by inactivating its tumor suppressive functions, and by conferring aberrant pro-carcinogenic activities. We report here that mis-sense mutants in the p53 DNA-binding domain (DBD) and the transactivation domain (TAD) unexpectedly activate...
ORGANISM(S): Homo Sapiens (human) 
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