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UnknownSex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine.
Not available
S-EPMC7360766 | biostudies-literature
TranscriptomicsTranscription profiling of human trabecular meshwork cultured cells, non-glaucomatous and POAG tissue
The goal of this study was to contrast genome-wide gene expression profiles of cultured human trabecular meshwork (HTM) cells, to that of control and primary open angle glaucoma (POAG) HTM tissues. Total RNA from cultured HTM cells and HTM tissue dissected from control and POAG anterior segments fix...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4316 | biostudies-arrayexpress
UnknownInvestigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.
Not available
S-EPMC2827864 | biostudies-literature
UnknownIdentification of two common variants contributing to serum apolipoprotein B levels in Mexicans.
Not available
S-EPMC2809779 | biostudies-literature
MetabolomicsIAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function
The islet in type 2 diabetes (T2D) is characterized by amyloid deposits derived from islet amyloid polypeptide (IAPP), a protein co-expressed with insulin by β-cells. In common with amyloidogenic proteins implicated in neurodegeneration, human IAPP (hIAPP) forms membrane permeant toxic oligomers imp...
2020-04-17 | MTBLS951 | MetaboLights
UnknownThe N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.
Not available
S-EPMC3148733 | biostudies-literature
MetabolomicsArginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Defective arginine synthesis, due to the silencing of argininosuccinate synthase 1 (ASS1), is a common metabolic vulnerability in cancer, known as arginine auxotrophy. Understanding how arginine depletion kills arginine-auxotrophic cancer cells will facilitate the development of anti-cancer therapeu...
2019-11-07 | MTBLS745 | MetaboLights
UnknownGenomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
Not available
S-EPMC3917605 | biostudies-literature
UnknownEvidence of how rs7575840 influences apolipoprotein B-containing lipid particles.
Not available
S-EPMC3081410 | biostudies-literature
UnknownGalanin preproprotein is associated with elevated plasma triglycerides.
Not available
S-EPMC2650822 | biostudies-literature
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