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TranscriptomicsNormal Lung + Lung adenocarcinoma microarray
Gene transcription in a set of 49 human primary lung adenocarcinomas and 9 normal lung tissue samples was examined using Affymetrix GeneChip technology. We aimed to investigate differential gene expression between the two tissue types. A total of 3,442 genes, called the set MAD, were found to be eit...
ORGANISM(S): Homo sapiens 
2005-12-31 | E-MEXP-231 | biostudies-arrayexpress
TranscriptomicsThe homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (microRNA)
Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcription factor Nkx2-1, essential for lung cell differentiation, mainly acts in transcriptional activation but can directly or indirectly repress gene expr...
ORGANISM(S): Mus musculus 
2015-12-22 | E-GEOD-47053 | biostudies-arrayexpress
TranscriptomicsThe homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (mRNA)
Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcription factor Nkx2-1, essential for lung cell differentiation, mainly acts in transcriptional activation but can directly or indirectly repress gene expr...
ORGANISM(S): Mus musculus 
2015-12-22 | E-GEOD-47054 | biostudies-arrayexpress
TranscriptomicsGrhl2 regulated genes in the mouse lung epithelial MLE15 cell line
The Grainyhead family of transcription factors controls morphogenesis and differentiation of epithelial cell layers in multicellular organisms by regulating cell junction- and proliferation-related genes. Grainyhead-like 2 (Grhl2) is expressed in developing mouse lung epithelium and is required for ...
ORGANISM(S): Mus musculus 
2012-09-10 | E-GEOD-40729 | biostudies-arrayexpress
TranscriptomicsGene amplification of the transcription factor DP1 and the CTNND1 in human lung cancer
The search for novel oncogenes is important because these could be the target of future specific anticancer therapies. In the present work, we report the identification of novel amplified genes in lung cancer. In order to find out novel amplified genes in lung cancer, we aligned the gene expression ...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-21168 | biostudies-arrayexpress
TranscriptomicsCharacterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.
To identify genes expressed during initiation of lung organogenesis, we generated transcriptional profiles of the prospective lung region of the mouse foregut (mid-foregut) microdissected from embryos at three developmental stages between embryonic day 8.5 (E8.5) and E9.5. This period spans from lun...
ORGANISM(S): Mus musculus 
2010-01-14 | E-GEOD-19873 | biostudies-arrayexpress
ProteomicsEngineered live bacteria suppress Pseudomonas aeruginosa lung infection in mouse and dissolve biofilm in endotracheal tubes from patients
Engineered live bacteria could provide a new modality for treating lung infections , a major cause of mortality worldwide. Here, we engineered a genome-reduced human lung bacterium, Mycoplasma pneumoniae, to treat ventilator-associated pneumonia (VAP), a disease with high hospital mortality when ass...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2023-10-24 | PXD037233 | Pride
Engineered live bacteria  pseudomonas aeruginosa  lung infection  mouse  biofilm  endotracheal tubes 
UnknownImplications of the Adiponectin System in Non-Small Cell Lung Cancer Patients: A Case-Control Study.
Not available
S-EPMC7356727 | biostudies-literature
TranscriptomicsInfection of chicken with avian influenza H5N1 and H5N2 viruses
Transcriptional profiling was carried out on lung and ileum samples at 1dpi and 3dpi from chickens infected with either low pathogenic (H5N2) or highly pathogenic (H5N1) avian influenza. Infected birds were compared to control birds at each time point.
ORGANISM(S): Gallus gallus 
2015-01-19 | E-MTAB-2908 | biostudies-arrayexpress
UnknownOne-Lung Ventilation and Postoperative Pulmonary Complications After Major Lung Resection Surgery. A Multicenter Randomized Controlled Trial.
Not available
S-EPMC10133024 | biostudies-literature
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