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ProteomicsThe microbiome of the lichen Lobaria pulmonaria varies according to climate in Europe
The Lobaria pulmonaria holobiont consists of algal, fungal, cyanobacterial, and integrated diverse bacterial components and thrives in undisturbed, humid forests. We set out to investigate the role of the microbiome of L. pulmonaria in the adaptation of this ecologically sensitive lichen species to ...
ORGANISM(S): Lobaria pulmonaria 
2024-07-03 | PXD049079 | Pride
Symbiosis Genotyping Lung lichen Holobiont Metaproteomics 
GenomicsMicrobiome Data of the Lung Lichen Lobaria pulmonaria
Symbiont-specific responses of the lung lichen holobiont to excess light and nitrogen
PRJEB86950 | ENA
TranscriptomicsIdentification of novel candidate target genes at 3q26.2-q29 in squamous cell carcinoma of the lung
High-resolution array-CGH was performed to identify differences in the patterns of genomic imbalances between SCC and AC of non-small cell lung cancer (NSCLC). On a genome-wide profile, SCCs showed higher frequency of gains than ACs (p = 0.067). More specifically, statistically significant differenc...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-16597 | biostudies-arrayexpress
TranscriptomicsSodium arsenite induced gene expression changes in A549 human epithelial lung carcinoma cells
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns which could lead to altered gene expression Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 ...
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44169 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung tissue from cardiac death and brain death donors, both pre and post transplant
Lung donation after cardiac death (DCD), in contrast to donation after brain death (DBD), is a promising and increasingly common method to help relieve the shortage of donor organs. However, the pathogenetic consequences of retrieved lungs after DCD vs. DBD have not been clarified. We aimed to study...
ORGANISM(S): Homo sapiens 
2009-11-11 | E-GEOD-18995 | biostudies-arrayexpress
TranscriptomicsSodium arsenite induced changes in A549 human epithelial lung carcinoma cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44174 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanism of phosgene-induced lung injury
Carbonyl chloride (phosgene) is a toxic industrial compound (TIC) widely used in industry for the production of synthetic products, such as polyfoam rubber, plastics, and dyes. Exposure to phosgene results in a latent (1-24 hr), potentially life-threatening pulmonary edema and irreversible acute lu...
ORGANISM(S): Mus musculus 
2007-06-25 | E-GEOD-2565 | biostudies-arrayexpress
UnknownAn acetonic extract and secondary metabolites from the endolichenic fungus Nemania sp. EL006872 exhibit immune checkpoint inhibitory activity in lung cancer cell.
Not available
S-EPMC9495263 | biostudies-literature
UnknownRhizobiales as functional and endosymbiontic members in the lichen symbiosis of Lobaria pulmonaria L.
Not available
S-EPMC4322706 | biostudies-literature
TranscriptomicsRNA-Seq of human bronchoalveolar lavage and lung biopsy samples in the segmental endotoxin challenge model
Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy can be used as a model to safely induce transient airway inflammation in the human lung. The LPS challenge model enables investigation of cellular mechanisms involved in pulmonary inflammatory processes as well as pharmacodynamic ana...
ORGANISM(S): Homo sapiens 
2024-03-01 | E-MTAB-13318 | biostudies-arrayexpress
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