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ProteomicsProteomic reveals reasons for acquired drug resistance in lung cancer derived brain metastasis based on a newly established multi-organ microfluidic chip model
Anti-tumor drugs can effectively shrink the lesions of primary lung cancer; however, it has limited therapeutic effect on patients with brain metastasis (BM). A BM preclinical model based on a multi-organ microfluidic chip has been established proficiently in our previous work. In this study, the BM...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021760 | Pride
Lung cancer  brain metastasis  microfluidic organ-on-a-chip  drug resistance  proteomic. 
TranscriptomicsChip-on-chip analysis of direct Nkx2.1 target genes in proliferating and differentiating epithelium in mouse lung development.
Nkx2.1 is a critical regulator of mammalian lung development. It is expressed in epithelial cells at the initiation of lung organogenesis, becoming progressively restricted during development to bronchiolar and alveolar type II epithelial cells. In humans, it is a common marker of carcinomas of lung...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-23043 | biostudies-arrayexpress
GenomicsA human alveolus-on-chip model for radiation induced lung injury
A human alveolus-on-chip model for radiation induced lung injury
PRJNA1014392 | ENA
GenomicsAn alveolus lung on a chip model of Mycobacterium fortuitum lung infection
An alveolus lung on a chip model of Mycobacterium fortuitum lung infection
PRJNA1154596 | ENA
GenomicsA human alveolus-on-chip model for studying radiation induced lung injury
A human alveolus-on-chip model for studying radiation induced lung injury
PRJNA1015133 | ENA
UnknownA human lung alveolus-on-a-chip model of acute radiation-induced lung injury.
Not available
S-EPMC10579267 | biostudies-literature
UnknownAdvanced Lung-on-a-Chip Technology: Mimicking the Complex Human Lung Microenvironment.
Not available
S-EPMC11667821 | biostudies-literature
UnknownExploratory Evaluation of EGFR-Targeted Anti-Tumor Drugs for Lung Cancer Based on Lung-on-a-Chip.
Not available
S-EPMC9405841 | biostudies-literature
UnknownA 3D human lung-on-a-chip model for nanotoxicity testing.
Not available
S-EPMC6220735 | biostudies-literature
UnknownDynamics of nanoparticles in a 3D breathing lung-on-a-chip.
Not available
S-EPMC12619719 | biostudies-literature
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