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ProteomicsComprehensive ubiquitomics characterization identify biomarkers of liver cancer subtypes
Hepatocellular carcinoma (HCC) has been widely studied at multi-omics level, but little is known about its specific ubiquitination, a major post-translational modification (PTM). In this study, we performed the ubiquitomics data collected from 85 HCC tumors and 18 adjacent normal tissues (ANTs) to e...
ORGANISM(S): Homo sapiens (Human) 
2025-04-07 | PXD047211 | Pride
Ubiquitomics  human  hcc 
ProteomicsComprehensive proteomics characterization identify biomarkers of liver cancer subtypes
Recurrence and metastasis remain the major obstacles to prognosis of hepatocellular carcinoma (HCC), but the relationship between proteomics and poor prognosis need to be studied more systematically. In this study, we performed the proteomics data collected from 85 HCC tumors and 18 adjacent normal ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-07 | PXD047168 | Pride
Proteomics  human  hcc 
ProteomicsComprehensive phosphoproteomics characterization identify drug targets of liver cancer
Recurrence and metastasis remain the major obstacles to prognosis of hepatocellular carcinoma (HCC), but the relationship between phosphoproteomics and drug targets need to be studied more systematically. In this study, we performed the phosphoproteomics data collected from 18 paired HCC patients to...
ORGANISM(S): Homo sapiens (Human) 
2025-04-07 | PXD047213 | Pride
Phosphoproteomics  human  hcc 
ProteomicsComprehensive proteometics identifies FBXL6 substrates involved in liver cancer
FBXL6 is frequently over-expressed in human hepatocellular carcinoma (HCC). However, it is still unknown the underlying mechanisms by which FBXL6 promotes HCC. In this study, we compared ubiquitinated protein profiles among a panel of liver tissue samples (including HCC, adjacent tissues and normal...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD032357 | Pride
Hcc Mice Fbxl6 
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