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TranscriptomicsInterleukin-10-anergized T-cell infusion provides immune reconstitution without severe graft-versus-host disease after haploidentical hematopoietic stem cell transplantation
Regulatory T cells restore tolerance in preclinical models of immune-mediated diseases and are therefore a promising alternative to conventional immune-suppression for preventing graft-versus-host disease (GvHD) in patients receiving allogeneic hematopoietic stem cell transplantation (HSCT). Adaptiv...
ORGANISM(S): Homo sapiens 
2015-12-14 | E-GEOD-21885 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of chronic antibody mediated rejection in kidney transplantation (mRNA CD4)
Chronic antibody-mediated rejection (CAMR) represents the main cause of kidney graft loss, but its pathogenesis is unclear. In order to uncover the molecular mechanisms underlying this condition, we characterized the molecular signature of circulating peripheral blood mononuclear cells and, separate...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-64261 | biostudies-arrayexpress
TranscriptomicsIL-7 and IL-15 instruct the generation of human memory stem T cells from naïve precursors
The identification of the most appropriate T-cell subset to ensure optimal persistence and anti-tumor activity is a major goal of cancer immunotherapy. We identified a novel post-mitotic CD45RA+CD62L+ T cell subpopulation (TTN), generated in vitro upon activation of naïve T (TN) cells with beads con...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-41909 | biostudies-arrayexpress
UnknownPartial Compensation of IL-17 Production by Vγ1 T Cells in the Absence of Vγ4 and Vγ6 T Cells.
Not available
S-EPMC12449965 | biostudies-literature
UnknownA Targeted Catalytic Nanobody (T-CAN) with Asparaginolytic Activity.
Not available
S-EPMC8616244 | biostudies-literature
UnknownReal-Time Imaging of Resident T Cells in Human Lung and Ovarian Carcinomas Reveals How Different Tumor Microenvironments Control T Lymphocyte Migration.
Not available
S-EPMC4600956 | biostudies-literature
UnknownImpaired Anti-Tumor T cell Response in Hepatocellular Carcinoma.
Not available
S-EPMC7139707 | biostudies-literature
TranscriptomicsMolecular characterization of chronic antibody mediated rejection in kidney transplantation (microRNA)
Chronic antibody-mediated rejection (CAMR) represents the main cause of kidney graft loss, but its pathogenesis is unclear. In order to uncover the molecular mechanisms underlying this condition, we characterized the molecular signature of circulating peripheral blood mononuclear cells and, separate...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-51676 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of chronic antibody mediated rejection in kidney transplantation (mRNA)
Chronic antibody-mediated rejection (CAMR) represents the main cause of kidney graft loss, but its pathogenesis is unclear. In order to uncover the molecular mechanisms underlying this condition, we characterized the molecular signature of circulating peripheral blood mononuclear cells and, separate...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-51675 | biostudies-arrayexpress
UnknownReceptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells.
Not available
S-EPMC3804130 | biostudies-literature
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