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TranscriptomicsGenetic homogeneity among strains of Clostridium botulinum type A1 with a unique toxin gene cluster organization
Comparative genomic hybridizations were performed to compare bont/A1 strains with an A2-like toxin gene cluster organization to the genome sequenced strain, C. botulinum ATCC 3502. Keywords: comparative genomic hybridization For each hybridization, the reference strain (C. botulinum ATCC 3502) was...
ORGANISM(S): Clostridium botulinum 
2010-05-26 | E-GEOD-10223 | biostudies-arrayexpress
TranscriptomicsUse of CGH microarrays to identify strain variable genomic regions in C. botulinum ATCC 3502
Comparative genomic hybridization microarrays featuring overlapping probes spanning the entire C. botulinum type A1 strain ATCC 3502 genome were used to identify regions whose presence are variable among a diverse panel of type A C. botulinum strains. For each hybridization, the reference strain (C....
ORGANISM(S): Clostridium botulinum 
2010-05-19 | E-GEOD-16010 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene content among Group II Clostridium botulinum strains
The purpose of this study was to compare the gene content of several group II C. botulinum strains to determine the utility of DNA microarrays for subtyping this organism. Group II type B, E, and F C. botulinum strains were compared in a study to examine the gene content of a unique type E strain (C...
ORGANISM(S): Clostridium botulinum 
2012-11-08 | E-GEOD-40271 | biostudies-arrayexpress
TranscriptomicsDetection and differentiation of Clostridium botulinum strains
Strains were differentiated on the basis of hybridization to probes representing strain variable regions in C. botulinum strain ATCC 3502. Probes for selected genes (eg. toxin genes) were also featured on the microarray to allow detection of other serotypes/subtypes. 44 strains were evaluated for s...
ORGANISM(S): Clostridium botulinum A str. ATCC 3502 
2010-05-18 | E-GEOD-16101 | biostudies-arrayexpress
TranscriptomicsFocused DNA microarray to differentiate Clostridium botulinum type A strains
Strains were differentiated on the basis of hybridization to probes representing strain variable regions in C. botulinum strain ATCC 3502. Probes for selected genes (eg. toxin genes) were also featured on the microarray to allow detection of other serotypes/subtypes. 27 strains were evaluated for se...
ORGANISM(S): Clostridium botulinum A str. ATCC 3502 
2010-05-05 | E-GEOD-18086 | biostudies-arrayexpress
TranscriptomicsGenomic content analysis of Clostridium botulinum type F strains
The purpose of this study was to determine the level of genomic content similarity among selected strains of Clostridium botuinum type F strains. In this study, strains were selected that had already been chacaterized by botulinum neurotoxin gene sequencing. Strains harboring bont/F1, bont/F4 and b...
ORGANISM(S): Clostridium botulinum 
2013-12-19 | E-GEOD-53456 | biostudies-arrayexpress
UnknownDual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF).
Not available
S-EPMC3746839 | biostudies-literature
UnknownClinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.
Not available
S-EPMC7666431 | biostudies-literature
UnknownImpact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial.
Not available
S-EPMC12824789 | biostudies-literature
UnknownOral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes: A Secondary Analysis of the SOUL Randomized Clinical Trial.
Not available
S-EPMC12865694 | biostudies-literature
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