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TranscriptomicsDifferential gene expression profiles between myeloid-biased and lymphoid-biased hematopoietic stem cells.
Array analysis of My-bi and Ly-bi HSC identifies candidate molecules for myeloid-bias. Collectively the data show that HSC in adults are largely epigenetically fixed in differentiation and self-renewal behavior. A direct examination of the epigenetic mechanisms that imprint HSC is difficult. However...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-41702 | biostudies-arrayexpress
ProteomicsM.barkeri with/without hematite/PCA
Paper title: The reduction of environmentally abundant iron oxides by the methanogen Methanosarcina barkeri Author List: Efrat Eliani-Russak, Zohar Tik, Shaked Uzi-Gavrilov, Michael M. Meijler and Orit Sivan Citation: Front. Microbiol. 14:1197299. doi: 10.3389/fmicb.2023.1197299 Brief description of...
ORGANISM(S): Methanosarcina Barkeri (ncbitaxon:2208) 
2024-12-29 | MSV000096740 | MassIVE
UnknownSequential Michael addition, cross-coupling and [3 + 2] cycloaddition reactions within the coordination sphere of chiral Ni(ii) Schiff base complexes derived from dehydroamino acids: pathways to the asymmetric synthesis of structurally diverse <i>O</i>-substituted serine and threonine analogs.
Not available
S-EPMC11969660 | biostudies-literature
TranscriptomicsHuman cell toxicogenomic analysis links reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts
The monohaloacetic acids (monoHAAs) are generated as byproducts during the disinfection of drinking water and are cytotoxic, genotoxic, mutagenic, and teratogenic. Iodoacetic acid (IAA) toxicity was mitigated by antioxidants, suggesting the involvement of oxidative stress. Other monoHAAs may share a...
ORGANISM(S): Homo sapiens 
2013-08-11 | E-GEOD-49698 | biostudies-arrayexpress
TranscriptomicsTranscriptional reprogramming of tumor-associated endothelial cells by disruption of TNF-M-NM-1 signaling
Endothelial inflammation contributes to the pathogenesis of numerous human diseases; however, the role of tumor endothelial inflammation in the growth of experimental tumors and its influence on the prognosis of human cancers is less understood. TNF-M-NM-1, an important mediator of tumor stromal inf...
ORGANISM(S): Mus musculus 
2012-10-20 | E-GEOD-33253 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse quantitative trait loci (QTLs) in uantitative trait loci (QTLs) and brain to identify genes and loci that control hematopoietic stem cell (HSC) functioning
We have combined large-scale mRNA expression and gene mapping methods to identify genes and loci that control hematopoietic stem cell (HSC) functioning. mRNA expression levels were measured in purified HSC isolated from a panel of densely genotyped recombinant inbred mouse strains. Quantitative trai...
ORGANISM(S): Mus musculus 
2007-11-16 | E-GEOD-2031 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of murine megakaryocyte progenitors (MkPs) from Cdk6 knockout and Cdk6 wild-type CALR-mutant mice
This experiment was performed to elucidate the effects of CDK6 on CALR-mutant Myeloproliferative Neoplasms. VavCre CALRdel52 knockin mice were crossed with full-body Cdk6-/- mice to obtain Cdk6-/- CALRdel52 mice. Bone marrow from mice of the four genotypes Cdk6+/+ CALR+/+ (wild-type), Cdk6+/+ CALRde...
ORGANISM(S): Mus musculus 
2026-08-03 | E-MTAB-15404 | biostudies-arrayexpress
ProteomicsClostridium autoethanogenum isopropanol production via native plasmid pCA replicon
Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon
ORGANISM(S): Clostridium Autoethanogenum (ncbitaxon:84023) 
2022-05-10 | MSV000089452 | MassIVE
GenomicsThe enhancer and promoter landscape of human regulatory and conventional T cell subpopulations
CD4+CD25+FOXP3+ human regulatory T cells (Treg) are essential for self-tolerance and immune homeostasis. Here, we generated genome-wide maps of poised and active enhancer elements marked by histone H3 lysine 4 monomethylation and histone H3 lysine 27 acetylation for CD4+CD25highCD45RA+ naive and CD4...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-43119 | biostudies-arrayexpress
UnknownSystematic evaluation of isoform function in literature reports of alternative splicing.
Not available
S-EPMC6114036 | biostudies-literature
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