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ProteomicsComparative analysis of proteomics between lymphocyte-rich hepatocellular carcinoma and hepatocellular carcinoma formalin fixed and paraffin embedded tissues
In this study, the proteomic tissue proteins were analyzed using LC-MS. Fifteen lymphocyte-rich HCC formalin fixed and paraffin embedded (FFPE) tissues, 15 adjacent normal FFPE tissues, and 15 HCC FFPE tissues were analyzed. More than 4,000 liver tissue proteins have been identified by high-sensitiv...
ORGANISM(S): Homo sapiens (Human) 
2024-02-21 | PXD037022 | Pride
Human Lc-msms Hepatocellular carcinoma Formalin fixed and paraffin embedded tissues Lymphocyte-rich hepatocellular carcinoma 
TranscriptomicsChip-chip from Hepatocellular carcinoma (HCC) specimens with H3K27me3
Epigenetic changes commonly occur in hepatocellular carcinoma (HCC) and are associated with aberrant gene expression. Recently, we demonstrated the pivotal role of abnormal H3K4me3 methylation, which is catalyzed by the menin/MLL, a TrxG family, in HCC development. Meanwhile, there is clear evidence...
ORGANISM(S): Homo sapiens 
2013-11-13 | E-GEOD-52301 | biostudies-arrayexpress
TranscriptomicsChip-chip from Hepatocellular carcinoma (HCC) specimens with H3K4me3
Epigenetic changes commonly occur in hepatocellular carcinoma (HCC) and are associated with aberrant gene expression. Recently, we demonstrated the pivotal role of abnormal H3K4me3 methylation, which is catalyzed by the menin/MLL, a TrxG family, in HCC development. Meanwhile, there is clear evidence...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-52190 | biostudies-arrayexpress
TranscriptomicsCpG site methylation of HCV-cirrhotic, HCV-HCC, and normal liver tissues
In this study we used a high-throughput method for assaying methylation of CpG sites simultaneously in a single sample for identifying differences in methylation observed in tissues ranging from normal liver to pre-neoplastic (cirrhosis) and neoplastic (HCC) states. Since there are important clinica...
ORGANISM(S): Homo sapiens 
2010-02-18 | E-GEOD-18081 | biostudies-arrayexpress
TranscriptomicsCrosstalk between very different family members: How STAT3 activating IL6-type cytokines inhibit the IFNg-like responses of IL27 in hepatocellular carcinoma cells
Interleukin-27 (IL27) is a type-I-cytokine of the IL6/IL12 family predominantly secreted by activated macrophages and dendritic cells. Best understood are the effects of IL27 on immune cells where it has been described to have pro- or anti-inflammatory properties, either promoting TH1 responses or s...
ORGANISM(S): Homo sapiens 
2017-07-05 | E-MTAB-4570 | biostudies-arrayexpress
TranscriptomicsIdentification of recurrence related microRNAs from bone marrow in hepatocellular carcinoma (HCC) patients
To identify the role of miRNAs in patient bone marrow (BM) and explore the function of these molecules during HCC progression, we employed microarray-based profiling to analyze miRNA expression in the BM of patients with HCC. MicroRNA expression in the BW of HCC patients was measured by using microa...
ORGANISM(S): Homo sapiens 
2015-08-06 | E-GEOD-71762 | biostudies-arrayexpress
UnknownApparent diffusion coefficient and tissue stiffness are associated with different tumor microenvironment features of hepatocellular carcinoma.
Not available
S-EPMC11519246 | biostudies-literature
UnknownNCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development.
Not available
S-EPMC6443584 | biostudies-literature
TranscriptomicsThe landscape of promoter DNA hypomethylation in liver cancer (MeDIP-chip data)
Extensive loss of DNA methylation is a hallmark of cancer. The role of hypomethylation in altering gene expression in cancer cells has been poorly understood. Hepatic cellular carcinoma (HCC) is one of the most common human cancers. We use HCC as a model to investigate hypomethylation in cancer by a...
ORGANISM(S): Homo sapiens 
2011-06-04 | E-GEOD-29720 | biostudies-arrayexpress
UnknownTumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment.
Not available
S-EPMC11849983 | biostudies-literature
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