Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human CD8 T cells in systemic lupus erythematosus (SLE) and vasculitis
Autoimmune diseases are common and debilitating, but their severe manifestations could be reduced if biomarkers were available to allow individual tailoring of the potentially toxic immunosuppressive therapy required for their control. Clinically useful biomarkers have been identified using DNA micr...
ORGANISM(S): Homo sapiens 
2010-06-02 | E-MTAB-157 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human separated leukocyte subsets in SLE and vasculitis
Objective: To optimize a strategy for identifying gene expression signatures differentiating SLE and anti-neutrophil cytoplasmic antibody-associated vasculitis that provide insight into the pathogenesis and identify biomarkers.
Methods: Forty four vasculitis patients, 13 SLE patients and 25 age...
ORGANISM(S): Homo sapiens 
2010-06-02 | E-MTAB-145 | biostudies-arrayexpress
TranscriptomicsAT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity
Purpose: Deregulated phosphatidylinositol 3-kinase pathway signaling through AGC kinases including AKT, p70S6 kinase, PKA, SGK and Rho kinase, is a key driver of multiple cancers. The simultaneous inhibition of multiple AGC kinases may increase antitumor activity and minimize clinical resistance com...
ORGANISM(S): Homo sapiens 
2012-07-19 | E-GEOD-38008 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peripheral blood leukocyte subsets in autoimmune/autoinflammatory disease patients and healthy controls
Gene expression microarray profiling was performed on peripheral blood leukocyte subsets (CD4+ T cells, CD14+ monocytes, and CD16+ neutrophils) from healthy controls and patients with flaring autoimmune disease.
ORGANISM(S): Homo sapiens 
2014-08-31 | E-MTAB-2452 | biostudies-arrayexpress
ProteomicsKetone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding
Time-restricted feeding (TRF) has gained attention as a dietary regimen that promotes metabolic health. This study sought to determine if ketone flux in skeletal and cardiac muscles plays an essential role in conferring the health benefits of an intermittent TRF (iTRF) schedule. Notably, we found th...
ORGANISM(S): Mus Musculus (mouse) 
2024-02-09 | PXD047114 | JPOST Repository
TranscriptomicsBMM_C3H/HeJ_LPS_timecourse
Bone marrow derived macrophages (BMM) total RNA from C3H/ARC mice extracted after stimulation by LPS at different time points. Each time point stimulated with 10ug/ml LPS from Salmonella minnesota for the time indicated. The RNA from each BMM stimulated time point was labeled with Cy3 and compared w...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-326 | biostudies-arrayexpress
TranscriptomicsBMM_BalbC_LPS_timecourse
Bone marrow derived macrophages (BMM) total RNA from C3H/ARC mice extracted after stimulation by LPS at different time points. Each time point stimulated with 10ug/ml LPS from Salmonella minnesota for the time indicated. The RNA from each BMM stimulated time point was labeled with Cy3 and compared w...
ORGANISM(S): Mus musculus 
2003-03-27 | E-GEOD-325 | biostudies-arrayexpress
TranscriptomicsBMM_C3H/ARC_LPS_timecourse
Bone marrow derived macrophages (BMM) total RNA from C3H/ARC mice extracted after stimulation by LPS at different time points. Each time point stimulated with 10ug/ml LPS from Salmonella minnesota for the time indicated. The RNA from each BMM stimulated time point was labeled with Cy3 and compared w...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-324 | biostudies-arrayexpress
UnknownEfficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials.
Not available
S-EPMC8802260 | biostudies-literature
UnknownEstimating the Risk of Severe Peanut Allergy Using Clinical Background and IgE Sensitization Profiles.
Not available
S-EPMC8974676 | biostudies-literature
Sort   by:  
 Page size