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Post-transcriptional RNA regulation is critical for the formation of primordial follicles, which determine female reproductive potential. Stress-induced disruptions in RNA metabolism are increasingly recognized as key factors impairing oogenesis, but the underlying mechanisms remain poorly understoo...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD058281 | Pride
This study employed tandem mass tag (TMT) quantitative proteomics to investigate the dose-dependent effects of Staphylococcus aureus virulence factor phenol-soluble modulin α3 (PSMα3) on the global protein expression profile of human macrophages. THP-1 monocytic cells were differentiated into macrop...
ORGANISM(S): Homo sapiens (Human) Staphylococcus aureus 
2026-01-29 | PXD073725 | Pride
A cell line representative of human high-grade serous ovarian cancer (HGSOC) should not only resemble its tumor of origin at the molecular level, but also demonstrate functional utility in pre-clinical investigations. Here we report the integrated proteomic analysis of 26 ovarian cancer cell lines, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080814 | MassIVE
The coronavirus disease 2019 (COVID-19) pandemic has devastated global health. Identifying key host factors essential for SARS-CoV-2 RNA replication is expected to unravel cellular targets for the development of broad-spectrum antiviral drugs which have been quested for the preparedness of future vi...
ORGANISM(S): Homo Sapiens 
2022-09-28 | PXD037068 |
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD045174 |
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