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The functional importance of gene enhancers in regulated gene expression is well established. In addition to widespread transcription of long non-coding RNA (ncRNA) transcripts in mammalian cells, bidirectional ncRNAs referred to as eRNAs are present on enhancers. However, it has remained unclear wh...
ORGANISM(S): Homo sapiens 
Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
PKA regulates metabolism adaptation by phosphorylating Rpd3/HDAC1
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-03-12 | PXD058634 | Pride
Predisposition to Alzheimer's disease (AD) may arise from lipid metabolism perturbation, however, the underlying mechanism remains elusive. Here, we identify ATAD3A, a mitochondrial AAA-ATPase, as a molecular switch that links cholesterol metabolism impairment to AD phenotypes. In neuronal models of...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-11 | PXD031523 | Pride
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