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MetabolomicsStreamlining LC-MS/MS Data Analysis in R with Open-Source *xcms* and *RforMassSpectrometry*: An End-to-End Workflow

Despite untargeted LC-MS/MS data being a powerful approach for large-scale metabolomics analysis, a significant challenge in the field lies in the reproducible and efficient analysis of such data, in particular. The power of R-based analysis workflows lies in their high customizability and adapta...

2024-08-26 | MTBLS8735 | MetaboLights
UnknownCharacterization of a novel activated Ran GTPase mutant and its ability to induce cellular transformation.
Not available
S-EPMC3408178 | biostudies-literature
UnknownDiscovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Not available
S-EPMC4232217 | biostudies-literature
UnknownThe RNA m5C modification in R-loops as an off switch of Alt-NHEJ.
Not available
S-EPMC10542358 | biostudies-literature
TranscriptomicsSingle cell analysis of macrophages exposed to beads coated with LPS from Salmonella enterica subsp. typhimurium
We present a detailed single cell analysis of the macrophage response to LPS from Salmonella enterica. By combining single cell transcriptional analysis, fluorescently labeled, LPS-coated beads, and cytometry we are able to distinguish the responses of macrophages that have internalized LPS-coated ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65529 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fibroblast-like synovial cells from normal adult horse following treatment with hyaluronan and challenged with lipopolysaccharide
Greater than 95% confluent (Day 0) fibroblast-like synovial cells from the hind limbs (pelvic limb) of normal adult horses were allocated in triplicate to one of 4 groups:

(group 1) unchallenged;
(group 2) LPS-challenged;
(group 3) LPS-challenged following pre-treatment and susta...
ORGANISM(S): Equus caballus 
2007-01-10 | E-MEXP-940 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung samples treated with Simvastatin and LPS and corresponded controls
This series contain mouse lung samples treated with Simvastatin and LPS and corresponded controls.
ORGANISM(S): Mus musculus 
2007-11-09 | E-GEOD-1871 | biostudies-arrayexpress
TranscriptomicsA comparative analysis of the transcriptome profiles of liver and muscle tissue in pigs divergent for feed efficiency
The aim of this experiment was to identify changes in gene expression in muscle and liver between pigs that were divergent in feed efficiency. The animals were selected from two different farms of origin. 48 animals were utilized in this study. Following slaughter RNA Total RNA was extracted from li...
ORGANISM(S): Sus scrofa 
2019-04-24 | E-MTAB-7435 | biostudies-arrayexpress
UnknownCloning and Functional Analysis of NoMYB60 Gene Involved in Flavonoid Biosynthesis in Watercress (Nasturtium officinale R. Br.).
Not available
S-EPMC9690578 | biostudies-literature
MetabolomicsReduced uremic metabolites are prominent feature of sarcopenia, distinct from antioxidative markers for frailty

Due to global aging, frailty and sarcopenia are increasing. Sarcopenia is defined as loss of volume and strength of skeletal muscle in elderlies, while frailty involves multiple domains of aging-related dysfunction, impaired cognition, hypomobility and decreased social activity. However, little i...

2022-10-19 | MTBLS3341 | MetaboLights
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