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ProteomicsQuantitative proteomic analysis of the role of knocking down NRP1 after OGD/R in primary renal tubular epithelial cells
Neuropilin-1 (NRP1), a co-receptor for various cytokines, including TGF-β, has been identified as a potential therapeutic target for fibrosis. However, its role and mechanism in renal fibrosis remains elusive. Here, we show that NRP1 is upregulated in distal tubular (DT) cells of patients with trans...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-03 | PXD052244 | Pride
Lysine crotonylation Nrp1 Chronic kidney disease Acute kidney injury Aerobic metabolism 
ProteomicsReproducible Workflow for Multiplexed Deep-Scale Proteome and Phosphoproteome Analysis of Tumor Tissues by Liquid Chromatography-Mass Spectrometry

Mertins P, Tang LC, Krug K, Clark DJ, Gritsenko MA, Chen L, Clauser KR, Clauss TR, Shah P, Gillette MA, et al., Nat Protoc. 2018 Jul 9. doi: 10.1038/s41596-018-0006-9

Here we present an optimized workflow for gl...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-30 | MSV000084265 | MassIVE
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
MetabolomicsGut microbial release of ferulic acid from germinated quinoa alleviates obesity-associated cognitive impairment via activation of PINK1/Parkin-mediated mitophagy in the hippocampus

Background Obesity is a major risk factor for cognitive impairment and related neurodegenerative disorders. Whole grains are rich in polyphenols and dietary fiber, and their consumption has been associated with improvements in obesity and cognitive deficits. Gut microbial genes encode enzymes tha...

2026-03-30 | MTBLS14185 | MetaboLights
UnknownRisk Factors for Loss to Follow-up of Elderly Patients After Hip Fracture Surgery: A Retrospective Cohort Study.
Not available
S-EPMC11365032 | biostudies-literature
MetabolomicsThe Formation of Phenol and Indole Flavor Substances in Stinky Tofu Brine Based on Metabolism of Aromatic Amino Acids

Understanding the formation mechanism of the flavor compounds in stinky tofu brine is crucial for controlling the flavor quality of Changsha stinky tofu. Dynamic changes in associated bacteria, enzymes, and differential metabolites in the metabolic pathway of aromatic amino acids in brine were in...

2026-03-20 | MTBLS2849 | MetaboLights
UnknownClinicopathologic characterization and abnormal autophagy of CSF1R-related leukoencephalopathy.
Not available
S-EPMC6886209 | biostudies-literature
UnknownRole of endoscopic retrograde cholangiopancreatography in the management of benign biliary strictures: What's new?
Not available
S-EPMC4766255 | biostudies-literature
UnknownImplantable Multifunctional Micro-Oxygen Reservoir System for Promoting Vascular-Osteogenesis via Remodeling Regenerative Microenvironment.
Not available
S-EPMC11744641 | biostudies-literature
ProteomicsProteomics of cyanidin 3-O-galactoside to alleviate LPS-induced inflammatory response in mammary epithelial cells of dairy goats
An in vitro mastitis cell model was constructed by treating mammary epithelial cells of dairy goats with LPS and intervening with cyanidin 3-O-galactoside as a way, to elucidate and explore the key mechanisms involved in the process of inflammation alleviation by cyanidin 3-O-galactoside.
ORGANISM(S): Capra hircus (Goat) 
2025-09-15 | PXD063072 | Pride
Cyanidin 3-o-galactoside Mammary epithelial cells of dairy goats Inflammatory response Lps 
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