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ProteomicsSubcellular Interactomes Revealed by Merging APEX with Cross-linking Mass Spectrometry
An integrating APEX proximity labeling and chemical cross-linking coupled with mass spectrometry (CXMS) platform named APEX-CXMS for spatially resolved subcellular interactome profiling in a high-throughput ma
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD033838 |
TranscriptomicsGenome-wide analysis of microRNA expression in Non-small Cell Lung Cancer
Analysis of NSCLC development at microRNA expression level. Results shows that has-miR-96 is significant up-regulated in the cancer tissue compared with the adjacent normal tissue. Illumina Human v2 MicroRNA expression beadchip Total microRNA obtained from 6 paired NSCLC cancer tissue and the adjac...
ORGANISM(S): Homo sapiens 
2012-09-16 | E-GEOD-29248 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in Non-small Cell Lung Cancer
Analysis of NSCLC development at gene expression level. Results shows that obvious activation of cell cycle pathway, and significant repression of cell-cell communication pathways. Illumina HumanHT-12 V4.0 expression beadchip Total RNA obtained from 6 paired NSCLC cancer tissue and the adjacent nor...
ORGANISM(S): Homo sapiens 
2012-09-16 | E-GEOD-29249 | biostudies-arrayexpress
TranscriptomicsMac-1 cells with SATB1 silencing vs control Mac-1 cells
Transcriptional profiling of primary cutaneous anaplastic large cell lymphoma cell line Mac-1 cells transduced with lenti-virus vector harboring shRNA against SATB1 gene comparing control untreated Mac-1 cells and Mac-1 cells transduced with scrambled shRNA, in which SATB1 expression is not affected...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-50916 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling In Murine Retina Neovascularization Models
In order to find out the vital genes during retinal neovascularization (RNV), we set up OIR (oxygen-induced retinopathy; induced with 75%±2% oxygen) and wild-type C57BL/6J murine models. We observed the retinal vascular growth process daily both in OIR and wild-type mice through retinal flat-mount,...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-38762 | biostudies-arrayexpress
ProteomicsProteomics of obstructed kidneys from patients with obstructive nephropathy and unilateral ureteral obstruction mice
Here, we performed proteomics of kidneys obtained from patients with obstructive nephropathy and healthy controls (n=11/8), or from unilateral ureteral obstruction (UUO) mice and sham mice (n=6/6). Proteomic measurement of all human kidney samples resulted in a total of 6089 proteins with an average...
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-01-08 | PXD039314 |
ProteomicsDDX1 Methylation Mediated MATR3 Splicing Regulates Intervertebral Disc Degeneration by Initiating Chromatin Reprogramming
Low back pain (LBP), often caused by intervertebral disc degeneration (IVDD), poses a major challenge in aging populations. DDX1, an RNA-binding protein, plays key roles in RNA metabolism but its function in IVDD remains unclear. We identify DDX1 as a non-histone substrate of lysine methyltransferas...
ORGANISM(S): Homo Sapiens 
2025-05-29 | PXD064432 |
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