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no omics definedTranscription profiling of Yersinia pestis wild type and phoP deletion strains
Microarrays were used to identify Y. pestis genes that are transcriptional targets of phoP. RNA samples were isolated from cultures of two isogenic Y. pestis strains, one carrying wild-type phoP (KIM6+) and the other carrying a deletion within phoP (KIM6+phoP(delta)), and their gene expression prof...
ORGANISM(S): Yersinia pestis 
2006-07-01 | E-MEXP-713 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse skeletal muscle
We generated skeletal muscle-specific knockout mice lacking the transcription factor Yin Yang 1 (YY1) and analyzed expression patterns in the skeletal muscle these mice. We used microarrays to detail the global programme of gene expression regulated by YY1. Wild type or knockout mice at 6 months wer...
ORGANISM(S): Mus musculus 
2012-06-29 | E-GEOD-39009 | biostudies-arrayexpress
no omics definedTranscription profiling of Yersinia pestis overexpressing phoP
Microarrays were used to identify Y. pestis genes that are differentially regulated under conditions of phoP overexpression. RNA samples were isolated from cultures of two isogenic Y. pestis strains, one overexpressing phoP (KIM10+phoP(delta)/PhoP) and the other not (KIM10+phoP(delta)/MMB67EH), and ...
ORGANISM(S): Yersinia pestis 
2006-07-01 | E-MEXP-712 | biostudies-arrayexpress
MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
TranscriptomicsAlterations in the gene expression profile in SKOV3 cells exposed to elaiophylin
Elaiophylin was screened and identified as a novel autophagy inhibitor, with significant antitumor efficacy as a single agent. To explore the mechanisms by which elaiophylin kills cancer cells, NimbleGen 12x135K microarrays were used to find the gene expression changes in SKOV3 cells treated with el...
ORGANISM(S): Homo sapiens 
2022-06-07 | GSE205529 | GEO
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownA new species of Rhododendron (Ericaceae) from Guizhou, China.
Not available
S-EPMC9849097 | biostudies-literature
UnknownTowards practical and robust DNA-based data archiving using the yin-yang codec system.
Not available
S-EPMC10766522 | biostudies-literature
ProteomicsSystematic and quantitative assessment of hydrogen peroxide reactivity with cysteines across human proteomes
Protein cysteinyl residues are the mediators of hydrogen peroxide (H2O2)-dependent redox signaling. However, site-specific mapping of the selectivity and dynamics of these redox reactions in cells poses a major analytical challenge. Here we describe a chemoproteomic platform to systematically and qu...
ORGANISM(S): Homo sapiens (Human) 
2017-08-25 | PXD007153 | Pride
Cysteine chemoproteomics 
UnknownMetabolic Signatures of Kidney Yang Deficiency Syndrome and Protective Effects of Two Herbal Extracts in Rats Using GC/TOF MS.
Not available
S-EPMC3789486 | biostudies-literature
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