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Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
We engineered a cell system in which the glutathione synthetase (GS) mutant was expressed that catalyzed the formation of a glutathione analogy from azido-alanine to profile changes of glutathionylome in CD38-overexpressing cells.
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD032233 | Pride
Glutathionylation is an important posttranslational modification that protects proteins from further oxidative damage as well as influencing protein structure and activity. In the present study, we demonstrate that the cysteine-42 residue in protein arginine N-methyltransferase 5 (PRMT5) is glutathi...
ORGANISM(S): Homo sapiens (Human) 
2020-09-02 | PXD020428 | Pride
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