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GenomicsPolycomb preferentially targets stalled promoters of coding and non-coding transcripts
The Polycomb group (PcG) and Trithorax group (TrxG) of proteins are required for stable and heritable maintenance of repressed and active gene expression states. Their antagonistic function on gene control, repression for PcG and activity for TrxG, is mediated by binding to chromatin and subsequent ...
ORGANISM(S): Drosophila melanogaster 
2010-12-21 | E-GEOD-24521 | biostudies-arrayexpress
UnknownA phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours.
Not available
S-EPMC6354023 | biostudies-literature
UnknownCardiovascular Outcomes in GRADE (Glycemia Reduction Approaches in Type 2 Diabetes: A Comparative Effectiveness Study).
Not available
S-EPMC10978227 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis roots - transcriptional and posttranscriptional regulation of transcription factor expression
Understanding how the expression of transcription factor (TF) genes is modulated is essential for reconstructing gene regulatory networks. There is increasing evidence that sequences other than upstream noncoding can contribute to modulating gene expression, but how frequently they do so remains unc...
ORGANISM(S): Arabidopsis thaliana 
2009-06-23 | E-GEOD-16468 | biostudies-arrayexpress
UnknownSex differences in atrial fibrillation in India: Insights from the Kerala-AF registry.
Not available
S-EPMC11730713 | biostudies-literature
UnknownPhenotypes of South Asian patients with atrial fibrillation and holistic integrated care management: cluster analysis of data from KERALA-AF Registry.
Not available
S-EPMC11609390 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis 8 GFP marked lines with 2-3 replicates were used to augment existing microarray expression profiles of the root
Transcriptional programs that regulate development are exquisitely controlled in space and time. Elucidating these programs that underlie development is essential to understanding the acquisition of cell and tissue identity. We present microarray expression profiles of a high resolution set of deve...
ORGANISM(S): Arabidopsis thaliana 
2008-06-16 | E-GEOD-8934 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis roots - time course expression analysis of the salt stress response
We performed a time course analysis (TC data set) of the response of whole seedling roots to 140mM NaCl at 5 time points after transfer (30 minutes, 1, 4, 16 and 32 hours). Cells are amazingly adept at integrating both external and internal cues to regulate transcriptional states. While internal pr...
ORGANISM(S): Arabidopsis thaliana 
2009-04-25 | E-GEOD-7642 | biostudies-arrayexpress
UnknownGlycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes.
Not available
S-EPMC9832916 | biostudies-literature
UnknownEfficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Not available
S-EPMC8693692 | biostudies-literature
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