Sort   by:  
 Page size 
ModelsCaruso2020 - Activation of the alternative complement pathway and effects on hemolysis
This model is based on the publication: Caruso A, Vollmer J, Machacek M, Kortvely E. "Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease." PLoS Comput Biol. 2020 Oct 2;16(10):e1008139. doi: 10.1371/journal.pcbi.1008139 Curation Comment: ...
2021-09-11 | MODEL2109110001 | BioModels
TranscriptomicsaCGH analyses of DSB-induced LOH in Blm-deficient mESCs
Genome modification in mouse embryonic stem cells (mESCs) has provided the versatile platform to analyzing gene functions in mammalian cells. Bloom helicase-deficient mESCs showed elevated rate of loss of heterozygosity (LOH) through mitotic recombination. By utilizing this characteristic of Blm de...
ORGANISM(S): Mus musculus 
2012-11-30 | E-MTAB-1116 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae sgs1 mutant and wild type strains grown under DNA damaging and control conditions
Wild type and sgs1 null yeast were grown under DNA damaging (with MMS) conditions or without treatment to log phase and their transcriptional profiles compared. The human aging diseases Werner and Bloom syndromes are a result of mutation of the WRN and BLM genes, respectively. The SGS1 gene of Sacch...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-07 | E-GEOD-423 | biostudies-arrayexpress
UnknownSuppression of the growth and metastasis of mouse melanoma by <i>Taenia crassiceps</i> and <i>Mesocestoides corti</i> tapeworms.
Not available
S-EPMC10987685 | biostudies-literature
TranscriptomicsDigital expression profiling identifies CDC5L, RECQL4, and CDK4 as potential oncogenes in a cohort of pediatric osteosarcoma tumours
Osteosarcoma is the most common malignancy of bone, and occurs most frequently in children and adolescents. Currently, the most reliable technique for prognostication is measuring histopathologic tumor necrosis following preoperative chemotherapy, and favourable prognosis is signified by 90% or grea...
ORGANISM(S): Homo sapiens 
2016-03-15 | E-GEOD-45275 | biostudies-arrayexpress
UnknownAcid-Base Control of Valency within Carboranedithiol Self-Assembled Monolayers: Molecules Do the Can-Can.
Not available
S-EPMC6350814 | biostudies-literature
GenomicsA POLD3/BLM dependent pathway handles DSBs in transcribed chromatin upon excessive RNA:DNA hybrids accumulation
Transcriptionally active loci are particularly prone to breakage and mounting evidence suggest that DNA Double-Strand Breaks arising in active genes are handled by a dedicated repair pathway, Transcription-Coupled DSB Repair (TC-DSBR), that entails R-loop accumulation and dissolution. Here, we uncov...
ORGANISM(S): Homo sapiens 
2022-04-13 | E-MTAB-11592 | biostudies-arrayexpress
TranscriptomicsDNA-damaging agent and immune inducer synergistically induced defence gene expression in Arabidopsis
We used microarrays to identify differentially expressed genes after DNA-damaging agent bleomycin (BLM) and/or immune inducer 2, 6-dichloroisonicotinic acid (INA) treatment. We focused on those genes that were synergistically induced by co-treatment (BLM+INA). Arabidopsis seedlings were treated with...
ORGANISM(S): Arabidopsis thaliana 
2013-11-14 | E-GEOD-44793 | biostudies-arrayexpress
UnknownCoordination of Rho GTPase activities during cell protrusion.
Not available
S-EPMC2885353 | biostudies-literature
UnknownPharmacokinetics-Pharmacodynamics of Enmetazobactam Combined with Cefepime in a Neutropenic Murine Thigh Infection Model.
Not available
S-EPMC7269482 | biostudies-literature
Sort   by:  
 Page size