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UnknownTopography, clinical, and genomic correlates of 5q myeloid malignancies revisited.
Not available
S-EPMC3341146 | biostudies-literature
ProteomicsMolecular and clinical analyses of PHF6 mutant myeloid neoplasia provide clues as to their pathogenesis and therapeutic targeting
PHF6 mutations (PHF6MT) are identified in various myeloid neoplasms (MN). However, little is known about the precise function and consequences of PHF6 in MN. Our comprehensive genomic analyses focused on three main findings. Firstly, we revealed a different pattern of genes correlating with PHF6MT i...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD042441 | Pride
Human Lc-msms Phf6 Aml 
TranscriptomicsEpigenome analysis of patients with various myeloid malignancies including differential levels of 5-hydroxymethylcytosine
TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The gene encoding TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity (CN-LOH) in patients with diverse myeloid...
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25706 | biostudies-arrayexpress
UnknownPerceptions of disease state, treatment outcomes, and prognosis among patients with myelodysplastic syndromes: results from an internet-based survey.
Not available
S-EPMC3228221 | biostudies-literature
TranscriptomicsRajala_et_al_2013
Large lymphocytic leukemia (LGL) is a chronic clonal lymphoproliferative disorder, characterized by expansion of cytotoxic CD8+ T-cells or NK-cells. We compared gene expression of 3 LGL leukemia patients with STAT3 mutation (Patients 1, 2, and 3), 3 LGL leukemia patients with STAT5b mutation (Patien...
ORGANISM(S): Homo sapiens 
2013-04-15 | E-MTAB-1611 | biostudies-arrayexpress
UnknownNew lesions detected by single nucleotide polymorphism array-based chromosomal analysis have important clinical impact in acute myeloid leukemia.
Not available
S-EPMC2773477 | biostudies-literature
UnknownA phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction.
Not available
S-EPMC4077078 | biostudies-literature
UnknownInborn errors of immunity underlie clonal T cell expansions in large granular lymphocyte leukemia.
Not available
S-EPMC12043085 | biostudies-literature
UnknownLong-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria.
Not available
S-EPMC3744747 | biostudies-literature
UnknownDeciphering treatment patterns in non-severe/moderate aplastic anemia: an international observational study.
Not available
S-EPMC10681892 | biostudies-literature
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