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UnknownTopography, clinical, and genomic correlates of 5q myeloid malignancies revisited.
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S-EPMC3341146 | biostudies-literature
ProteomicsMolecular and clinical analyses of PHF6 mutant myeloid neoplasia provide clues as to their pathogenesis and therapeutic targeting
PHF6 mutations (PHF6MT) are identified in various myeloid neoplasms (MN). However, little is known about the precise function and consequences of PHF6 in MN. Our comprehensive genomic analyses focused on three main findings. Firstly, we revealed a different pattern of genes correlating with PHF6MT i...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD042441 | Pride
Human Lc-msms Phf6 Aml 
TranscriptomicsEpigenome analysis of patients with various myeloid malignancies including differential levels of 5-hydroxymethylcytosine
TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The gene encoding TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity (CN-LOH) in patients with diverse myeloid...
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25706 | biostudies-arrayexpress
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