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TranscriptomicsInfant high grade gliomas comprise multiple subgroups characterised by novel targetable gene fusions and better survival
Methylation array profiling of infant high grade gliomas identifies an intrinsic group of tumours with epigenetic profiles distinct from gliomas in older children. These tumours are characterised by very few recurrent mutations and carry a very high frequency of fusion genes. They can be diagnosed a...
ORGANISM(S): Homo sapiens 
2019-08-12 | E-MTAB-7804 | biostudies-arrayexpress
TranscriptomicsInfant high grade gliomas comprise multiple subgroups characterised by novel targetable gene fusions and better survival
Methylation array profiling of infant high grade gliomas identifies an intrinsic group of tumours with epigenetic profiles distinct from gliomas in older children. These tumours are characterised by very few recurrent mutations and carry a very high frequency of fusion genes. They can be diagnosed a...
ORGANISM(S): Homo sapiens 
2019-08-09 | E-MTAB-7802 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver with CEBPa wild type and knockout animals.
Expression analysis of CEBPa knockout effects on gene expression in adult mouse liver. We used a conditional knock out strategy to delete CEBPa specifically in adult mouse hepatocytes and analysed the resulting changes in gene expression by means of microarrays.
ORGANISM(S): Mus musculus 
2010-04-08 | E-MTAB-178 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of human olfactory neurosphere-derived cell lines from healthy and idiopathic Parkinsons disease individuals.
The human olfactory epithelium represents a readily accessible source of adult neural cell types which can be propagated in vitro. We have used this feature to establish olfactory neurosphere-derived (hONS) cells lines from patients with idiopathic Parkinson's disease (PD) and healthy controls. We i...
ORGANISM(S): Homo sapiens 
2011-07-14 | E-TABM-879 | biostudies-arrayexpress
GenomicsChIP-seq of Canis familiaris, Gallus gallus, Mus musculus, Homo sapiens, Monodelphis domestica to investigate CEBPA and HNF4a binding in five vertebrates
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of trancription factor binding. The SRF files for this experiment can be found in the European Read Archive with study accession number ERP000054. The fastq files can be found in the raw archives and for some assays links to the ENA runs and...
ORGANISM(S): Canis familiaris 
2010-04-08 | E-TABM-722 | biostudies-arrayexpress
GenomicsWhole genome sequencing of tumour and normal paired samples of diffuse intrinsic pontine gliomas
Diffuse intrinsic pontine glioma (DIPG) have a universally dismal prognosis (median 9-12 months), with neither chemotherapeutic nor targeted agents showing any substantial survival benefit in clinical trials in children with these tumours. DIPG are highly infiltrative malignant glial neoplasms of th...
EGAS00001000572 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:22:20:271-113 - samples
Whole exome sequencing of 6 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000706 | EGA
Genomicsena-DATASET-INSTITUTE OF CANCER RESEARCH-17-12-2013-15:02:33:112-168 - samples
Whole genome sequencing of 20 tumour and normal pairs of diffuse intrinsic pontine glioma (DIPG)
EGAD00001000705 | EGA
GenomicsICR DIPG Data Access Committee
Data Access Committee EGAC00001000148
EGAC00001000148 | EGA
UnknownChildhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.
Not available
S-EPMC4567699 | biostudies-literature
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