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The relationship between dyslipidemia and type 2 diabetes mellitus (T2D) has been extensively reported, but the global lipid profiles, especially in the East Asia population, associated with the development of T2D remain to be characterized. Liquid chromatography coupled to tandem mass spectromet...

2017-04-26 | MTBLS352 | MetaboLights
Obesity impairs tissue insulin sensitivity and signaling, promoting type-2 diabetes. Although improving insulin signaling is key to reversing diabetes, the multi-organ mechanisms regulating this process are poorly defined. We screened the secretome and receptome in Drosophila to identify the hormona...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-27 | PXD053061 | Pride
Low-density lipoprotein receptor (LDLR) and LDLR-related proteins (LRPs) are essential endocytic receptors and regulators of multiple physiological processes including protein reabsorption, cholesterol clearance, and neuronal protein trafficking. Previously, we identified O-GalNAc glycans within lig...
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD058370 | Pride
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