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TranscriptomicsDemethyl fructiculin A (SCO-1) induces apoptosis by inducing reactive oxygen species in mitochondria
Demethyl fructiculin A is a diterpenoid quinone component of the exudates from Salvia corrugata (SCO-1) leafes. SCO-1 was recently reported to induce anoikis in mammalian cell lines via a molecular mechanism involving the presence of the membrane scavenging receptor CD36. However, experiments perfor...
ORGANISM(S): Homo sapiens 
2010-10-15 | E-GEOD-19846 | biostudies-arrayexpress
TranscriptomicsThe gamma secretase inhibitor LLNle induces apoptosis of human GBM tumor initiating cells
Glioblastomas (GBM) are poorly differentiated astrocytic tumors arising in the Central Nervous System (CNS), which despite aggressive treatments are still characterized by a fatal outcome. Several studies have shown the existence of a subpopulation of cells within glioma tumors displaying cancer ste...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-14581 | biostudies-arrayexpress
UnknownPreoperative Assessment and Management of Cardiovascular Risk in Patients Undergoing Non-Cardiac Surgery: Implementing a Systematic Stepwise Approach during the COVID-19 Pandemic Era.
Not available
S-EPMC8541645 | biostudies-literature
UnknownPlazomicin against Multidrug-Resistant Bacteria: A Scoping Review.
Not available
S-EPMC9784334 | biostudies-literature
UnknownPrognostic Value of Coronary Calcium Score in Asymptomatic Individuals: A Systematic Review.
Not available
S-EPMC9573072 | biostudies-literature
ProteomicsMass spectrometry analysis of the Skp1 and Cullin1 interactome in Leishmania infantum
Leishmania infantum is the causative agent of visceral leishmaniasis in Latin America, a lethal disease if misdiagnosed or left untreated. The ubiquitin proteasome system (UPS) is the main regulator of intracellular proteolysis in eukaryotes and is required for parasite's to life cycle and infectio...
ORGANISM(S): Leishmania infantum 
2024-07-01 | PXD051961 | Pride
Ap-ms Cullin-1-ring ubiquitin ligases (crl1) E3 ubiquitin ligases Leishmania infantum 
UnknownTechnical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.
Not available
S-EPMC11384460 | biostudies-literature
UnknownHigh-flux hemodialysis with polymethylmethacrylate membranes reduces soluble CD40L, a mediator of cardiovascular disease in uremia.
Not available
S-EPMC12559792 | biostudies-literature
UnknownFunctional characterization of Cullin-1-RING ubiquitin ligase (CRL1) complex in Leishmania infantum.
Not available
S-EPMC11285970 | biostudies-literature
UnknownLung Recruitment Before Surfactant Administration in Extremely Preterm Neonates: 2-Year Follow-Up of a Randomized Clinical Trial.
Not available
S-EPMC11425149 | biostudies-literature
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