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Previous studies have investigated the peptidomic changes occurring in cow milk during mastitis; however, these focused mainly on clinical mastitis, either spontaneous (Mansor et al., 2013) or induced by experimental infection (Thomas et al., 2016). Mansor and coworkers were the first to use mass sp...
ORGANISM(S): Bos taurus (Bovine) 
2020-07-15 | PXD017768 | Pride
A shotgun label-free quantitative proteomic approach was utilized to compare the peptidome of plasma samples from healthy and hemorrhagic shock pigs to verify the possible role of uncontrolled proteolytic activity in shock.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-09-08 | PXD008018 | Pride
Emerging evidence suggests that sex-specific differences in L-serine (L-Ser) metabolism play a key role in Alzheimer’s disease (AD). While disruptions in amino acid balance are well known, recent findings point to a dimorphic regulation of the serine biosynthetic pathway. To explore this, we examine...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD072965 | Pride
Mutations in collagen I account for the most frequent cause of the skeletal disease osteogenesis imperfecta (OI) and are responsible for delay in protein folding and synthesis of molecules with abnormal structure. A fraction of aberrant collagen molecules is secreted in the extracellular matrix (ECM...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-13 | PXD059591 | Pride
Astrocytes are essential players in brain development and functions, being particularly relevant as regulators of energy metabolism, ionic homeostasis, and synaptic transmission. They are also the major source of L-serine (L-Ser) in the brain, which is synthesized from the glycolytic intermediate 3-...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD045073 | Pride
Collagen misfolding, reduced collagen secretion and incorporation into the extracellular matrix, and impaired collagen organization are common features both in a physiological condition like aging and in pathological conditions like genetic diseases caused by defects in collagen or collagen related ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD047320 | Pride
abundance based on iBAQ, Interaction consistency score: 6.0, Coverage: 7
ORGANISM(S): 9685 
2021-00-00 | 1049965078 | PAXDB
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-14 | MSV000081329 | MassIVE
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-30 | MSV000081121 | MassIVE
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