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Decremental loss of PTEN results in cancer susceptibility and tumor progression. In turn this raises the possibility that PTEN elevation might be an attractive option for cancer prevention and therapy. We have generated several transgenic mouse lines with variably elevated PTEN expression levels, ta...
ORGANISM(S): Mus musculus 
Tumor stroma strongly influences behaviour of cancer cells. Here, we study influence of the tumor stroma on transcription activity of head and neck squamous cell carcinoma cells. In particular, we compare transcription activity of the cancer cells in relation to expression of a putative prognostic m...
ORGANISM(S): Homo sapiens 
Tumor stroma strongly influences behaviour of cancer cells. Here, we study influence of the tumor stroma on transcription activity of head and neck squamous cell carcinoma cells. In particular, we compare transcription activity of the cancer cells in relation to expression of a putative prognostic m...
ORGANISM(S): Homo sapiens 
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