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ProteomicsMechanism of antimicrobial synergy between doxycycline and carprofen against methicillin-resistant Staphylococus pseudintermedius
We previously showed that doxycycline and carprofen , a veterinary non-steroidal anti-inflammatory drug, have synergistic antimicrobial activity against methicillin-resistant Staphylococus pseudintermedius (MRSP) carrying the tetracycline resistance determinant TetK. To elucidate the molecular mecha...
ORGANISM(S): Staphylococcus pseudintermedius 
2020-05-26 | PXD013725 | Pride
Antimicrobial resistance 2d dige 
UnknownComputational Approach to Dendritic Spine Taxonomy and Shape Transition Analysis.
Not available
S-EPMC5180374 | biostudies-literature
UnknownThe cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines.
Not available
S-EPMC8847666 | biostudies-literature
UnknownImpaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome.
Not available
S-EPMC10665894 | biostudies-literature
ProteomicsMass spectrometry analysis of synaptic proteome of adult Fmr1 KO and wild-type mice.
Fragile X syndrome (FXS) is the most common monogenetic cause of inherited intellectual disability and autism in humans. One of the well-characterized molecular phenotypes of Fmr1 KO mice, a model of FXS, is increased translation of synaptic proteins. Although this upregulation stabilizes in the adu...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD043700 | Pride
Brain Synaptoneurosomes Fmr1 ko mice 
UnknownDisrupting interaction between miR-132 and Mmp9 3'UTR improves synaptic plasticity and memory in mice.
Not available
S-EPMC9389266 | biostudies-literature
UnknownThree-Dimensional Segmentation and Reconstruction of Neuronal Nuclei in Confocal Microscopic Images.
Not available
S-EPMC6710455 | biostudies-literature
UnknownMutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males.
Not available
S-EPMC11554806 | biostudies-literature
ProteomicsMolecular mechanism of resilience in stress-related disorders
Stress resilience is a dynamic process whereby an individual can withstand stressful events while still maintaining normal, physiological functioning. Resilience is inferred from an observed level of cognitive performance higher than expected in the face of a demonstrated stressful event. The neural...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD026590 | Pride
Depression Cus model 
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