Sort   by:  
 Page size 
TranscriptomicsRegulatory T cell modulation by CBP/EP300 bromodomain inhibition [array]
Genome-wide gene expression changes in response to CBP inhibitor treatment in Treg cells using microarray. Expression profiling by microarray of Treg cells treated with DMSO or CBP inhibitor, and Th0 cells
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-66596 | biostudies-arrayexpress
TranscriptomicsT cell UTX promotes Tfh-mediated clearance of persistent virus infection
Epigenetic changes, including histone methylation, control T cell differentiation and memory formation, though the enzymes that mediate these processes are not clear. We show that UTX, a histone H3 lysine 27 (H3K27) demethylase, promotes the generation of T follicular helper (Tfh) cells, a CD4+ T ce...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-64969 | biostudies-arrayexpress
UnknownUTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability.
Not available
S-EPMC8112613 | biostudies-literature
GenomicsUTX constrains antiviral CD8+ T cell responses during chronic virus infection
UTX constrains antiviral CD8+ T cell responses during chronic virus infection
PRJNA601463 | ENA
UnknownObesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection.
Not available
S-EPMC6652206 | biostudies-literature
GenomicsObesity expands a distinct population of adipose-resident T cells and increases vulnerability to infection
Obesity expands a distinct population of adipose-resident T cells and increases vulnerability to infection
PRJNA433181 | ENA
UnknownT Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.
Not available
S-EPMC4731234 | biostudies-literature
UnknownMolecular and functional mapping of EED motifs required for PRC2-dependent histone methylation.
Not available
S-EPMC2693252 | biostudies-literature
GenomicsThe histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation
Here we show that T-box proteins team up with chromatin modifying enzymes to drive the expression of the key lineage regulator, Eomes during endodermal differentiation of embryonic stem (ES) cells. The Eomes locus is maintained in a transcriptionally poised configuration in ES cells. During early di...
ORGANISM(S): Mus musculus 
2013-04-18 | E-GEOD-44764 | biostudies-arrayexpress
UnknownLaboratory correlates for a phase II trial of romidepsin in cutaneous and peripheral T-cell lymphoma.
Not available
S-EPMC2838427 | biostudies-literature
Sort   by:  
 Page size