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ProteomicsKCC2 Proteome - Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition
KCC2 is a neuron-specific K+-Cl‑ cotransporter essential for establishing the Cl- gradient required for hyperpolarizing inhibition. KCC2 is highly localized to excitatory synapses where it regulates spine morphogenesis and AMPA receptor confinement. Aberrant KCC2 function contributes to numerous hum...
ORGANISM(S): Mus musculus (Mouse) 
2017-10-16 | PXD006046 | Pride
Kcc2 Interacting proteins Cation chloride cotransporter Lc/ms Proteomics Neuronal chloride homeostasis Slc12a5 Gaba E/i balance Glutamate 
UnknownSample size requirement for achieving multisite harmonization using structural brain MRI features.
Not available
S-EPMC7615107 | biostudies-literature
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