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ProteomicsComprehensive identification of proteins from MALDI imaging
MALDI imaging mass spectrometry (MALDI IMS) is a powerful tool for the visualization of proteins in tissues and has demonstrated considerable diagnostic and prognostic value. One main challenge is that the molecular identity of such potential biomarkers mostly remains unknown. We introduce a metho...
ORGANISM(S): Homo sapiens (Human) 
2013-07-03 | PXD000125 | Pride
Matrix and tissue proteome 
ProteomicsSegal_TMT_14-3-3_APMS_BioID_interactors
This dataset consists of 36 raw MS files acquired on Lumos Fusion Orbitrap mass spectrometer operated in Data Dependent Acquisition mode for TMT-10plex. The files are associated with a manuscript submitted for publication by Segal et al. that determines the protein-protein and proximity interactio...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-12 | MSV000089463 | MassIVE
TranscriptomicsTranscription profiling of human TK6 cells transduced with an oncoretrovirus expressing MDR1 (TK6MDR1) was vs untransduced TK6 cells and to TK6 cell transduced with an oncoretrovirus expressing the Neomycin resistance gene (TK6neo)
Gene expression of TK6 cells transduced with an oncoretrovirus expressing MDR1 (TK6MDR1) was compared to untransduced TK6 cells and to TK6 cell transduced with an oncoretrovirus expressing the Neomycin resistance gene (TK6neo). Two biological replicates of each were generated and the expression prof...
ORGANISM(S): Homo sapiens 
2005-09-15 | E-MEXP-428 | biostudies-arrayexpress
UnknownThe heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.
Not available
S-EPMC3578922 | biostudies-literature
ProteomicsComparative proteomic and transcriptomic analysis of the impact of androgen stimulation and darolutamide inhibition on prostate cancer cells
Androgen receptor (AR) signaling is a major driver and therapy target in prostate cancer. Several inhibitors of AR function are approved for different stages of the disease and their impact on downstream gene transcription has been described. However, the ensuing effects of androgen and anti-androge...
ORGANISM(S): Homo sapiens (Human) 
2023-02-17 | PXD036962 | Pride
Andrigen receptor signalling Vcap Darolutamide 
TranscriptomicsHigh-resolution chromosomal maps of Xist RNA reveal a two-step spreading mechanism during X-inactivation
The Xist long noncoding RNA (lncRNA) is essential for X-chromosome inactivation (XCI), the process by which mammals compensate for unequal numbers of sex chromosomes. During XCI, Xist coats the future inactive X (Xi) and recruits Polycomb Repressive Complex 2 (PRC2) to the X-inactivation center (Xic...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-48649 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Arabidopsis 4 day-old light-treated seedlings using anti H3, CT, pan, anti H3K9me2 and IgG antibodies
ChIP was performed using 100 mg of 4 day-old light-treated seedlings. The following antibodies were used: anti H3, CT, pan (Millipore 07-690), anti H3K9me2 (Diagenode pAb-060-050) and IgG (Sigma I50006).
ORGANISM(S): Arabidopsis thaliana 
2009-12-08 | E-MEXP-2480 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of pancreatic cancer cell line that differ in metastatic potential
Two pancreatic cancer cell lines with different metastatic and growth potential were compared under hypoxic conditions and under normal atmospheric oxygen pressure. The FG cell lines shows very few metastases and slow growth in mouse xenograft models. L3.6pl, derived from FG by cycles re-implantatio...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-9350 | biostudies-arrayexpress
UnknownMetalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo.
Not available
S-EPMC3149364 | biostudies-literature
UnknownAnalysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
Not available
S-EPMC10181183 | biostudies-literature
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