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TranscriptomicsTranscription profiling of mouse olfactory epithelium frpm Harlequin mutants compared to littermate controls
Microarray analysis of gene expression in the olfactory epithelium of Harlequin mouse as a model of oxidative-stress induced neurodegeneration of olfactory sensory neurons Experiment Overall Design: Olfactory epithelium from Harlequin mutant mice and littermate control mice was microdissected for RN...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6485 | biostudies-arrayexpress
TranscriptomicsAnalysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation
Artificial transcription factors (ATFs) and genomic nucleases based on a DNA binding platform consist- ing of multiple zinc finger domains are currently be- ing developed for clinical applications. However, no genome-wide investigations into their binding speci- ficity have been performed. We have c...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-59980 | biostudies-arrayexpress
UnknownStrategies for treating acute pain in patients with opioid dependence: a scoping review protocol.
Not available
S-EPMC10860028 | biostudies-literature
Transcriptomics24 Hour Response of M. tuberculosis Erdman TMCC 107 to 20 micromolar clofazimine
3 sets of CFZ-exposed bacteria were compared to 3 sets of bacteria treated with vehicle (DMSO) for 24 hours in an aerated drug killing model.
ORGANISM(S): Mycobacterium tuberculosis 
2020-07-22 | E-MTAB-9350 | biostudies-arrayexpress
TranscriptomicsFNR- vs WT in anoxic conditions
Salmonella enterica var. Typhimurium (S. Typhimurium) is a Gram-negative, facultative intracellular pathogen that infects the intestinal tracts of humans and animals. In the host, S. Typhimurium encounters a wide range of oxygen concentrations going from oxic conditions in the stomach to near anoxic...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2010-07-01 | E-GEOD-3657 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of Salmonella during lag, exponential and stationary phases of growth
Transcriptional profiles during all phases of growth of Salmonella Typhimurium SL1344 were obtained and used to investigate growth phase-dependent alterations in gene expression. Viable count growth curve analysis of the growth system showed a culture lag time of 2.09 hours, and profiles at 4, 20, 4...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2011-12-13 | E-GEOD-22294 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology
Background: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal-offspring bond and is often accompanied by housing. While mu...
ORGANISM(S): Bos taurus 
2012-06-25 | E-GEOD-37447 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of zebrafish mononuclear myogenic cells (zMNCs) during myogenic differentiation
Analysis of the transcriptome of zebrafish mononuclear myogenic cells (zMNCs) during myogenic differentiation. The main goal is to identify the similarities of zMNC myogenic differentiation with that of mammalian myoblast differentiation. Critical time points were used to identify a switch from the ...
ORGANISM(S): Danio rerio 
2010-04-07 | E-GEOD-19754 | biostudies-arrayexpress
TranscriptomicsGene expression comparison among spleen dendritic cells, brain microglia, brain dendritic cells and bone marrow monocytes
To understand the functional relationship between brain dendritic cells (brain DCs) and other myeloid cells, we compared the gene expression profile of m/chDCs to that of bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. In order to obtain enough brain DCs for mRNA extr...
ORGANISM(S): Mus musculus 
2011-06-22 | E-GEOD-29949 | biostudies-arrayexpress
TranscriptomicsTranscription profiling timecourse of aging human myotubes cultured in low or high glucose medium
Aging of skeletal muscle tissue is characterized by loss of metabolic and contractile competence. It is thought that this phenomenon is driven via extrinsic and intrinsic factors. In order to identify age-dependent changes intrinsic to the muscle cell, microarray transcriptional profiles and measure...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1144 | biostudies-arrayexpress
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