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MetabolomicsMAVEN2: An Updated Open-Source Mass Spectrometry Exploration Platform

MAVEN, an open-source software program for analysis of LC-MS metabolomics data, was originally released in 2010. As mass spectrometry has advanced in the intervening years, MAVEN has been periodically updated to reflect this advancement. This manuscript describes a major update to the program, MA...

2024-07-22 | MTBLS3097 | MetaboLights
TranscriptomicsThe anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria
Protein synthesis by ribosomes takes place on a linear substrate but at variable speeds. Transient pausing of ribosomes can impact a variety of co-translational processes, including protein targeting and folding. These pauses are influenced by the sequence of the mRNA. Thus redundancy in the genetic...
ORGANISM(S): Escherichia coli 
2012-04-01 | E-GEOD-35641 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of Entamoeba histolytica Mutant Derived from Virulent Strain
Amoebiasis is a disease caused by the protozoan parasite, Entamoeba histolytica, with or without clinical symptoms . It has been suggested that pathogenic amoebae use three major virulence factors: Gal/GalNAc lectin, cysteine proteinases and amoebapores. However, these molecules cannot exclusively ...
ORGANISM(S): Entamoeba histolytica 
2015-05-15 | E-MTAB-3525 | biostudies-arrayexpress
Methylation profiling[E-TABM-482] DNA methylome of human spermatozoa
Genome-wide DNA methylation profile of human spermatozoa using the meDIP technique and massively parallel sequencing. DNA methylation is an indispensible epigenetic modification required for regulating the expression of mammalian genomes. Immunoprecipitation-based methods for DNA methylome analysis ...
ORGANISM(S): Homo sapiens 
2011-02-05 | GSE25686 | GEO
MetabolomicsDT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates

Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy approved. A major hurdle in NASH drug development is the poor translatability of preclinical studies to safe/effective clinical outcomes, and recent failures highlight a need to identify new targetable pathways. Dysr...

2023-04-13 | MTBLS5005 | MetaboLights
UnknownImproved methods and resources for paramecium genomics: transcription units, gene annotation and gene expression.
Not available
S-EPMC5485702 | biostudies-literature
UnknownEEG-based brain connectivity and sentiment analysis from smartphone social communication: insights into remitted major depressive disorder among adolescents.
Not available
S-EPMC12504114 | biostudies-literature
UnknownStructure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site.
Not available
S-EPMC1569165 | biostudies-literature
UnknownMaking and breaking symmetry in development, growth and disease.
Not available
S-EPMC6737901 | biostudies-literature
TranscriptomicsDevelopmental stage-specific gene expression in the two-spotted spider mite (Tetranychus urticae)
We generated 77-bp Illumina reads from single messenger RNA libraries from four diverse developmental stages of the two-spotted spider mite to maximally capture the complement of transcribed sequences across development. Adult, nymphal, larvae and embryonic stages were separated using sieves of vari...
ORGANISM(S): Tetranychus urticae 
2011-11-23 | E-GEOD-31527 | biostudies-arrayexpress
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