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The ability of RNAs to form specific contacts with other macromolecules provides an important mechanism for subcellular compartmentalization. We developed a suite of hybridization-proximity (HyPro) labeling technologies for unbiased discovery of proteins (HyPro-MS) and transcripts (HyPro-seq) associ...
ORGANISM(S): Homo sapiens (Human) 
2021-11-08 | PXD025264 | Pride
Proteins co-localizing with RNA targets of interest in HeLa cells were identified using our recently optimized hybridization-proximity labeling approach (HyPro2) combined with label-free mass spectrometry. Briefly, fixed and permeabilized cells were hybridized with digoxigenin-labeled antisense olig...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD063191 | Pride
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