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ProteomicsCardioprotection by selective SGLT2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?
Major clinical trials with sodium glucose co-transporter-2 inhibitors (SGLT-2i) exhibit protective effects against heart failure events, whereas inconsistencies regarding the cardiovascular death outcomes are observed. Therefore, we aimed to compare the selective SGLT-2i empagliflozin (EMPA), dapagl...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-17 | MSV000088582 | MassIVE
ProteomicsLC-MS/MS based proteomics analysis of decellularized and non-decellularized mouse kidney tissue samples
Two C57Bl6/J male mice were sacrificed by injecting 200 microliters of the lethal anaesthetic Dolethal. Kidneys were perfused with Dulbeccos Phosphate Buffered Saline, dissected, decapsulated and weighted. Kidneys were decellularized using 3 freeze-thaw cycles (freezing at -80C, 30 minute long thawi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-02-07 | MSV000094031 | MassIVE
ProteomicsProteomic dataset of exosomes derived from fetal mesenchymal stromal cells
The raw files of the proteomics dataset are N=18 and a brief description of the files is shown below: AF1 raw: exosomes derived from Amniotic Fluid-Mesenchymal Stromal cells 1 AF2.raw: exosomes derived from Amniotic Fluid-Mesenchymal Stromal cells 2 AFA1.raw: exosomes derived from Amniotic Fl...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092848 | MassIVE
ProteomicsHUVEC cell extracts for the investigation of collagen-induced cell signalling
We demonstrated that an abundant Collagen type I alpha 1-derived peptide inhibited collagen type I-induced endothelial cell migration in Human Umbilical Vein Endothelial Cells. We then applied mass spectrometry based proteomics to investigate the potential signalling pathways induced by collagen typ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-03-12 | MSV000097296 | MassIVE
ProteomicsProteomic analysis of bone marrow CD138+ cells to identify proteins associated with the response of multiple myeloma patients to commonly used therapeutic regimens.
Multiple Myeloma (MM) remains incurable; gaps in our understanding of MM molecular pathogenesis and drugs resistance mechanisms are involved in the failure of therapies to eradicate the disease. This study aims to identify proteins significantly impacting MM patients' response to commonly used thera...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-04-02 | MSV000097497 | MassIVE
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