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Transmission of malaria is dependent on the successful completion of the Plasmodium lifecycle in the Anopheles vector. Major obstacles are encountered in the midgut tissue, where most parasites are killed by the mosquito’s immune system. In the present study, DNA microarray analyses have been used t...
ORGANISM(S): Anopheles gambiae 
C-mannosylation stabilizes proteins bearing a thrombospondin repeat (TSR) domain in metazoans. Here we show that Plasmodium falciparum expresses a DPY19 C-mannosyltransferase in the endoplasmic reticulum and that DPY19-deficiency abolishes C-glycosylation, destabilizes members of the TRAP adhesin fa...
ORGANISM(S): Plasmodium falciparum 
2022-07-06 | PXD033470 | Pride
P. falciparum ookinetes were generated by in vitro culture methods and analyzed by DDA LC-MS.
ORGANISM(S): Plasmodium falciparum 
2025-07-21 | PXD060734 | Pride
Gene expression during the late ookinete and oocyst stages of Plasmodium falciparum (human malaria parasite) development has not been previously described in detail. We used single-cell RNA-seq to map gene expression changes in both parasite and mosquito cells and their interactions at multiple time...
ORGANISM(S): Anopheles gambiae Plasmodium falciparum 
2025-08-18 | GSE284537 | GEO
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