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MalariaM-bM-^@M-^Ys cycle of infection requires parasite transmission between a mosquito vector and a vertebrate host. Plasmodium regulates transmission by translationally repressing specific mRNAs until their products are needed. We demonstrate that the Plasmodium yoelii Pumilio-FBF family member P...
ORGANISM(S): Plasmodium yoelii yoelii 17XNL 
Sporozoite-specific genes were induced in parasites that express AP2-O whose AP2 domain was swapped with that of AP2-Sp. DNA construct encoding AP2 domain of AP2-Sp was introduced into P. bergei schizonts. It was integrated into the locus of the endogenious AP2-O gene, resulting in swap of the AP2-...
ORGANISM(S): Plasmodium berghei 
The goal of OOCYSTOP is based on an innovative concept to block malaria transmission by development of new drugs that will be delivered (1) to oocysts in infected mosquitoes and (2) to early stages in human infection by the sporozoite
ORGANISM(S): Plasmodium Berghei Anka (ncbitaxon:5823) 
2023-02-28 | MSV000091377 | MassIVE
Whole sporozoite proteins of Eimeria acervulina were prepared and analyzed by 2-dimensional gel electrophoresis (2-DE) followed by Western blotting using immune sera specific to E. tenella, E. acervulina, or E. necatrix.
ORGANISM(S): Eimeria acervulina 
2020-05-27 | PXD016418 | Pride
Cryptosporidium is a leading cause of diarrheal disease in children and an important contributor to early childhood mortality. The parasite invades intestinal epithelial cells and remodels them extensively including building an elaborate interface structure. How this occurs at the molecular level is...
ORGANISM(S): Cryptosporidium parvum virus 1 Cryptosporidium parvum Iowa II 
2023-03-30 | PXD038366 | Pride
The apicomplexan parasite Toxoplasma gondii has a complex life cycle involving multiple host species. Access to sexual stages and sporozoite-containing oocysts, essential for the parasite’s environmental transmission, is limited and requires animal experiments with cats. In vitro alternatives and re...
ORGANISM(S): Toxoplasma gondii Homo sapiens (Human) 
2025-05-07 | PXD055279 | Pride
Genome-wide investigation of transcriptional regulation in malaria sporozoite [RNA-Seq]
Malaria’s cycle of infection requires parasite transmission between a mosquito vector and a vertebrate host. Plasmodium regulates transmission by translationally repressing specific mRNAs until their products are needed. We demonstrate that the Plasmodium yoelii Pumilio-FBF family member Puf2 allows...
ORGANISM(S): Plasmodium yoelii yoelii 17XNL 
2012-10-27 | GSE41873 | GEO
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