Sort   by:  
 Page size 
GenomicsChip-Seq analysis of human chromosome 21 after its passage through either the female or male mouse germline
This study aims to investigate whether the passage of human chromosome 21 through the mouse male germline results in changes in the transcriptional deployment of the exogenous chromosome in the offspring generation. We used the Tc1 mouse model that stably carries almost an entire copy of human chrom...
ORGANISM(S): Mus musculus 
2016-11-16 | E-MTAB-4913 | biostudies-arrayexpress
GenomicsBioCAP-Seq analysis of human chromosome 21 after its passage through either the mouse male germline
This study aims to investigate whether the passage of human chromosome 21 through the mouse male germline results in changes in the transcriptional deployment of the exogenous chromosome in the offspring generation. We used the Tc1 mouse model that stably carries almost an entire copy of human chrom...
ORGANISM(S): Mus musculus 
2016-11-16 | E-MTAB-4930 | biostudies-arrayexpress
TranscriptomicsRNA-Seq in liver of Tc1 mice carrying human chromosome 21 passaged through either the female or male germline
This study aims to investigate whether the passage of human chromosome 21 through the mouse male germline results in changes in the transcriptional deployment of the exogenous chromosome in the offspring generation. We used the Tc1 mouse model that stably carries almost an entire copy of human chrom...
ORGANISM(S): Mus musculus 
2016-11-16 | E-MTAB-4912 | biostudies-arrayexpress
ProteomicsOmega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice
Soybean oil consumption is increasing worldwide and parallels the rise in obesity. Rich in unsaturated fats, especially linoleic acid, soybean oil is assumed to be healthy, and yet it induces obesity, diabetes, insulin resistance and fatty liver in mice. Here, we show that the genetically modified s...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-06-08 | MSV000081149 | MassIVE
TranscriptomicsTranscription profiling of mouse liver genomic responses to ciguatoxin (P-CTX-1)
Ciguatoxins (CTX) are polyether neurotoxins responsible for ciguatera, the most common fish-borne food poisoning in humans. This study characterizes the global transcriptional response of mouse liver to a symptomatic dose (0.26 ng/g) of the highly potent Pacific ciguatoxin-1 (P-CTX-1). At 1 h post...
ORGANISM(S): Mus musculus 
2008-06-20 | E-GEOD-10768 | biostudies-arrayexpress
UnknownValidation of the knowledge evaluation questionnaire of the cardiopulmonary resuscitation training program in high school students.
Not available
S-EPMC10589594 | biostudies-literature
TranscriptomicsImpact of aging on cell-to-cell transcriptional variability during immune stimulation
We explored how aging impacts transcriptional dynamics using single-cell RNA-sequencing to profile hundreds of CD4+ T cells from young and old mice from two divergent species. In young animals, immunological challenge drives a conserved transcriptomic switch from highly variable to tightly regulated...
ORGANISM(S): Mus musculus 
2016-07-21 | E-MTAB-4888 | biostudies-arrayexpress
TranscriptomicsDevelopmental transcriptional profiling of Triticeae reproductive development
Despite their importance, there remains a paucity of large scale expression-based studies of reproductive development in the species belonging to the Triticeae. As a first step to address this deficiency, a gene expression atlas of triticale reproductive development was generated using the 55K Affy...
ORGANISM(S): Triticum turgidum subsp. durum x Secale cereale 
2012-11-01 | E-GEOD-41984 | biostudies-arrayexpress
GenomicsA Population Genomics Study Using a Disease-Targeted Cell model: Integration of cis-eQTLs Discovered in Human Primary Osteoblasts with GWAS of Bone Phenotypes

The common genetic variants associated with complex traits typically lie in non-coding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quanti...

phs000225.v1.p1 | EGA
UnknownSex-related differences in the presentation, management and response to treatment of eosinophilic esophagitis: Cross sectional analysis of EoE CONNECT registry.
Not available
S-EPMC11652331 | biostudies-literature
Sort   by:  
 Page size