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TranscriptomicsSalmonella Typhimurium systemic infection of Ity14 mice (spleen tissue)
Salmonella-related infections outcome are dependent on the complex interaction between environmental factors, bacterial serotype and host genetic factors. Using ENU chemical mutagenesis, we identified a pedigree named Immunity to Typhimurium 14 (Ity14) carrying a mutation in Stat4 (c.1335+5G>A). Her...
ORGANISM(S): Mus musculus 
2014-05-06 | E-MTAB-1931 | biostudies-arrayexpress
TranscriptomicsGene Expression in AJ and AcB60 mice following Salmonella infection
Analysis of differential genome-wide gene expression within the splenic homogenate of A/J and AcB60 mice, both naïve mice and those infected with Salmonella Typhimrium Total RNA was islolated from the splenic homogenate of naïve A/J and AcB60 mice, as well as mice infected with 1000 CFUs of Salmonel...
ORGANISM(S): Mus musculus 
2015-02-12 | E-GEOD-65893 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis to evaluate the function of USP18 in the mouse CNS
Microglia are tissue macrophages of the central nervous system (CNS) that control tissue homeostasis, and as such they are crucially important for organ integrity. Microglia dysregulation is thought to be causal for a group of neuropsychiatric, neurodegenerative and neuroinflammatory diseases, calle...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-61499 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis to evaluate the role of USP18 in primary microglia and the microglia cell line BV-2
Microglia are tissue macrophages of the central nervous system (CNS) that control tissue homeostasis, and as such they are crucially important for organ integrity. Microglia dysregulation is thought to be causal for a group of neuropsychiatric, neurodegenerative and neuroinflammatory diseases, calle...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-61500 | biostudies-arrayexpress
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