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A variety of high-throughput techniques are now available for constructing comprehensive gene regulatory networks in systems biology. In this study, we report a new statistical approach for facilitating in silico inference of regulatory network structure. The new measure of association, coefficient ...
ORGANISM(S): Homo sapiens 
Genome wide of 5-hydroxymethylcytosine profiling of normal and abnormal, and globozoospermia sperm genomes.Two semen samples were collected from a healthy man and a globozoospermia patient who had consulted a physician at ShengJing Hospital of China Medical University. Other semen samples obtained f...
ORGANISM(S): Homo sapiens 
Increasing evidence has demonstrated that tumor-initiating cells (TICs) contribute to tumor initiation and therapy resistance through dysregulation of kinase signaling. However, the intertwined networks of many kinases and their functional downstream targets are yet to be revealed and fully characte...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD067039 | Pride
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis. Using breast cancer cell lines as a model system, we sought to discover gene-expression signatures of ...
ORGANISM(S): Homo sapiens 
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