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ProteomicsAltered Transcription Factor Expression Responses to Exercise in Insulin Resistance
Purpose. Insulin resistant muscle is resistant to gene expression changes induced by acute exercise. This study was undertaken to identify transcription factors that differentially respond to exercise in insulin resistance. Candidate transcription factors were identified from analysis of 5’-untransl...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023354 | Pride
Insulin resistance Skeletal muscle Exercise Gene expression Transcription factors 
TranscriptomicsGene and MicroRNA Expression Responses to Exercise; Relationship with Insulin Sensitivity
Healthy individuals on the lower end of the insulin sensitivity spectrum also have a reduced gene expression response to exercise for specific genes. The goal of this study was to determine the relationship between insulin sensitivity and exercise-induced gene expression in an unbiased, global manne...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-66334 | biostudies-arrayexpress
TranscriptomicsIncreases in Insulin Sensitivity among Obese Youth are Associated with Gene Expression Changes in Whole Blood.
Lifestyle intervention can improve insulin sensitivity in obese youth yet few studies have examined the biological mechanisms underlying improvements. Therefore, the purpose of this study was to explore biological pathways associated with intervention-induced improvements in insulin sensitivity. Fif...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-50800 | biostudies-arrayexpress
TranscriptomicsHuman skeletal muscle - type 2 diabetes and family history positive individuals - Mexican American
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic beta-cell dysfunction. In high-risk subjects, the earliest detectable abnormality is insulin resistance in skeletal muscle. Impaired insulin-mediated signaling, gene expression, and glycogen synthesis, and accumulati...
ORGANISM(S): Homo sapiens 
2010-04-27 | E-GEOD-21340 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle from diabetic or non-diabetic Mexican Americans with or without a family history of diabetes
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic beta-cell dysfunction. In high-risk subjects, the earliest detectable abnormality is insulin resistance in skeletal muscle. Impaired insulin-mediated signaling, gene expression, and glycogen synthesis, and accumulati...
ORGANISM(S): Homo sapiens 
2007-06-28 | E-CBIL-28 | biostudies-arrayexpress
TranscriptomicsmRNA changes induced by acute exercise
The purpose of this experiment was to determine what gene expression changes are induced by acute exercise in humans, and how those changes relate to insulin sensitivity 14 subjects had muscle biopsies at rest and 30 minutes after a single exercise bout for measurement of mRNA changes. Glucose clamp...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-43219 | biostudies-arrayexpress
UnknownDonepezil delays progression to AD in MCI subjects with depressive symptoms.
Not available
S-EPMC2697965 | biostudies-literature
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