Sort   by:  
 Page size 
GenomicsA transcription factor based mechanism for mouse heterochromatin formation
We identify Pax3 and Pax9 transcription factors (TFs) as important regulators of mouse heterochromatin. Simultaneous depletion of these factors results in loss of H3K9me3 from Major Satellite repeats and dramatic transcript overexpression. H3K9me3 enrichment at intergenic major satellite repeats is ...
ORGANISM(S): Mus musculus 
2012-09-16 | E-GEOD-40086 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse ES cells depleted of MOF, MSL1, MSL2 or KANSL3
We have studied the regulatory potential of MYST1-(MOF)-containing MSL and NSL complexes in mouse embryonic stem cells (ESCs) and neuronal progenitors. We find that both complexes influence transcription by binding to promoters as well as TSS-distal enhancer regions. In contrast to flies, the MSL co...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-57698 | biostudies-arrayexpress
TranscriptomicsSuv39h-dependent H3K9me3 represses intact retrotransposons in mouse embryonic stem cells
Heterochromatin is required to restrict aberrant expression of retrotransposons, but it remains poorly defined due to the underlying repeat-rich sequences. We dissected Suv39h-dependent histone H3 lysine 9 trimethylation (H3K9me3) by genome-wide ChIP-sequencing in mouse embryonic stem cells (ESCs). ...
ORGANISM(S): Mus musculus 
2014-06-26 | E-GEOD-57092 | biostudies-arrayexpress
TranscriptomicsATAC-seq of Mus musculus embryonic cell types in response to Pbx1 knockout
ATAC-seq was performed, mapped, and analyzed as previously described (PMID: 34446717: \\"ATAC-seq was performed on 50,000 cells per replicate as described in Buenrostro et al. (with modifications based on Corces et al.), on EpiSCs and PSM-differentiated cell populations at desired time-points. Libra...
ORGANISM(S): Mus musculus 
2023-12-01 | E-MTAB-13407 | biostudies-arrayexpress
GenomicsChIP-Seq of fly Schneider S2 cells to investigate CID islands
The centromere-specific Histone H3-variant CENH3 (also known as CENP-A) is considered to be an epigenetic mark for establishment and propagation of centromere identity. Pulse-induction of CENH3 (Drosophila CID) in Schneider S2 cells incorporates into noncentromeric regions and generates CID islands ...
ORGANISM(S): Drosophila melanogaster 
2011-07-15 | E-MTAB-652 | biostudies-arrayexpress
UnknownMOF maintains transcriptional programs regulating cellular stress response.
Not available
S-EPMC4893634 | biostudies-literature
UnknownA Radical-Cationic Covalent Organic Framework to Accelerate Polysulfide Conversion for Long-Durable Lithium-Sulfur Batteries.
Not available
S-EPMC12395410 | biostudies-literature
TranscriptomicsAnalysis of MOF under stress conditions
We analyzed the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin. Mof was deleted in MEFs using the Cre-ERT2 trasgene, while Mof was knockdown in podocytes using shRNA infection. Samples were treated with Adriamycin for 24 hours and gene expression changes analysed....
ORGANISM(S): Mus musculus 
2015-07-10 | E-GEOD-70706 | biostudies-arrayexpress
ProteomicsStress granules proteome composition
Analysis of stress granules in HeLa cells, after exposure to different stimuli. Granules were collected by a newly devised enrichment method, described in manuscript. Proteomics sample preparation of granules was carried out using the Single-pot, solid phase-enhanced sample preparation, SP3 method (...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-02 | MSV000090634 | MassIVE
GenomicsChIP-seq of MOF, MSL and NSL complex members in mouse ES cells and neuronal progenitors
We assessed the genome-wide binding of the histone acetylase MOF and members of its two associated complexes, the male-specific lethal and the non-specific lethal complex (MSL, NSL). We generated ChIP-seq profiles for MOF, MSL1, MSL2, KANSL3, and MCRS1 from mouse embryonic stem cells and neuronal pr...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-51746 | biostudies-arrayexpress
Sort   by:  
 Page size