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MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
UnknownRole of monoamine-oxidase-A-gene variation in the development of glioblastoma in males: a case control study.
Not available
S-EPMC6856259 | biostudies-literature
MetabolomicsThe Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas
B7H3 (also known as CD276) is a co-stimulator checkpoint protein of the cell surface B7 superfamily. Recently, the function beyond immune regulation of B7H3 has been widely studied. However, the expression preference and the regulation mechanism underlying B7H3 in different subtypes of gliomas is ra...
2021-05-26 | MTBLS2692 | MetaboLights
TranscriptomicsTranscription profiling of human pre-malignant breast cancer samples
Enlargement of normal terminal duct lobular units (TDLUs) by hyperplastic columnar epithelial cells is one of the most common abnormalities of growth in the adult female human breast. These hyperplastic enlarged lobular units (HELUs) are important clinically as the earliest histologically identifia...
ORGANISM(S): Homo sapiens 
2009-04-23 | E-GEOD-7377 | biostudies-arrayexpress
UnknownComparative analysis of REG{gamma} expression in mouse and human tissues.
Not available
S-EPMC2915620 | biostudies-literature
UnknownImmunomodulatory Effects of N-Acetyl Chitooligosaccharides on RAW264.7 Macrophages.
Not available
S-EPMC7460392 | biostudies-literature
UnknownAI-MARRVEL - A Knowledge-Driven AI System for Diagnosing Mendelian Disorders.
Not available
S-EPMC11221788 | biostudies-literature
UnknownPTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1.
Not available
S-EPMC10924424 | biostudies-literature
UnknownDrosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance.
Not available
S-EPMC6749836 | biostudies-literature
UnknownDe novo variants in MRTFB have gain-of-function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features.
Not available
S-EPMC11533975 | biostudies-literature
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