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TranscriptomicsRNA-seq of wild-type and Epas1 enhancer 5 (mm10 chr17: 86,801,737-86,802,738) knockout mouse mature adipocytes in normoxia and hypoxia and treated/untreated with CL 316243 β3-adrenoceptor agonist (thermogenesis inducer)
Epas1 Enhancer 5 [mm10 chr17: 86,801,737-86,802,738] (PMID: 36417539) was deleted in C57BL/6J mice and mature adipocytes differentiated from subcutaneous fat pads were kept in hypoxia (1% O2) and normoxia and treated with the CL 316243 β3-adrenoceptor agonist to induce thermogenesis. mRNA was collec...
ORGANISM(S): Mus musculus 
2026-10-19 | E-MTAB-17112 | biostudies-arrayexpress
GenomicsRole of Fnr1 and Fnr3 in transcriptional regulation under oxygen limitation in Herbaspirillum seropedicae
To determine the direct promoter targets of Fnr proteins, we correlated transcriptional changes observed in single fnr1 and fnr3 mutants (E-MTAB-5741) with ChIP-Seq analysis, taking advantage of C-terminally 3xFlag fnr alleles engineered into the H. seropedicae genome. ChIP-seq data were obtained fr...
ORGANISM(S): Herbaspirillum seropedicae 
2018-02-26 | E-MTAB-6395 | biostudies-arrayexpress
TranscriptomicsWWOX interacts with SMAD3 and modulates its transcriptional activity in breast cells
WWOX expression is lost during tumor progression in many human malignancies including breast cancer. To understand the effects of loss of WWOX expression we analyzed the consequences of its silencing in normal human breast cells (MCF10F). WWOX silencing led to the formation of larger cell colonies, ...
ORGANISM(S): Homo sapiens 
2013-11-28 | E-GEOD-47371 | biostudies-arrayexpress
UnknownTransforming jet flavour tagging at ATLAS.
Not available
S-EPMC12804921 | biostudies-literature
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