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ProteomicsMapping the tRNA Modification Landscape of Bartonella henselae Houston I and Bartonella quintana Toulouse
Transfer RNA (tRNA) modifications play a crucial role in maintaining translational fidelity and efficiency, and they may function as regulatory elements in stress response and virulence. Despite their pivotal roles, a comprehensive mapping of tRNA modifications and their associated synthesis genes i...
ORGANISM(S): Bartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae) Bartonella quintana str. Toulouse 
2024-01-23 | PXD048805 | Pride
Trna modification Intracellular pathogens Mass spectrometry Next-generation sequencing. 
ProteomicsEffect of rRNA methylation defect on protein composition of human ribosomes
Ribosomal RNAs (rRNAs) are main effectors of mRNA decoding, peptide-bond formation and ribosome dynamics during translation. Ribose 2'-O-methylation is the most abundant rRNA chemical modification, and display a complex pattern in rRNA. We globally challenged rRNA 2'-O-Me by inhibiting the rRNA meth...
ORGANISM(S): Homo sapiens (Human) 
2018-04-09 | PXD007244 | Pride
Ribosomes Fibrillarin Nanolc-ms/ms 
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