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ProteomicsA proteomic approach for unravelling the relevance of the polyadenylation factor EhCFIm25 in Entamoeba histolytica survival and virulence
Please provide an overall description of your study, think something similar in scope to the manuscript abstractCFIm25 is essential for recruitment of other polyadenylation factors, poly(A) site selection, pre-mRNA cleavage and poly(A) tail synthesis. We recently reported that EhCFIm25 silencing in ...
ORGANISM(S): Entamoeba histolytica HM-1:IMSS-A 
2021-08-26 | PXD027784 | Pride
Lc-msms I.e. human Plntamoeba histolytica  cfim25 silencing  polyadenylation  proteomics  virulenceasma Liver 
ProteomicsEntamoeba histolytica nuclear proteome
The polyadenylation factor EhCFIm25 has been recently reported as a biochemical target in Entamoeba histolytica. The prediction and experimental characterization of its interactome revealed close relationships between proteins involved in gene expression regulation and enzymes of energy metabolism. ...
ORGANISM(S): Entamoeba histolytica HM-1:IMSS-A 
2025-06-09 | PXD056950 | Pride
Entamoeba histolytica 
ProteomicsComparative genomics and interactomics of polyadenylation factors for the prediction of new parasite targets: Entamoeba histolytica as a working model
E. histolytica trophozoites (3x105) harvested in exponential growth phase were transferred to 25 cm² cell culture flasks and grown at 37°C for 24 h. Then, parasites were exposed to irradiation in a 254 nm UV-transilluminator (BioDoc-It Imaging System (UVP)) for 30 min at 4°C (Valdés et al., 2014) an...
ORGANISM(S): Entamoeba histolytica HM-1:IMSS-A 
2023-03-11 | PXD033620 | Pride
Mrna processing  protein-protein interactions  entamoeba histolytica 
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