Sort   by:  
 Page size 
ProteomicsCharacterization of cerebrospinal fluid via data-independent acquisition mass spectrometry
Cerebrospinal fluid (CSF) is in direct contact with the brain and serves as a valuable specimen to examine diseases of the central nervous system through analyzing its components. These include the analysis of metabolites, cells as well as proteins. For identifying new suitable diagnostic protein bi...
ORGANISM(S): Homo sapiens (Human) 
2018-09-17 | PXD010698 | Pride
Cerebrospinal fluid Dia Proteomics Data-independent acquisition mass spectrometry Csf Spectral library 
ModelsBucher2011_Atorvastatin_Metabolism
This is the model of atorvastatin metabolism in hepaitc cells described in the article: A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes Joachim Bucher , Stephan Riedmaier , Anke Schnabel , Katrin Marcus , G...
2024-09-02 | BIOMD0000000328 | BioModels
ProteomicsPIA - iPRG2008 Benchmark Dataset
This dataset is no actual new study but the iPRG2008 benchmark dataset used in the PIA manuscript.
ORGANISM(S): Mus musculus (Mouse) 
2015-05-08 | PXD000793 | Pride
Mouse Iprg2008 Benchmark 
ProteomicsReproducibility, specificity and accuracy of DIA quantification - Spectral Libraries
For the complete description see the manuscript. Data dependent acquisition (DDA) is the method of choice for mass spectrometry based proteomics discovery experiments, data-independent acquisition (DIA) is steadily becoming more important. One of the most important requirement to perform a DIA analy...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-08 | PXD012987 | Pride
Dia Label-free quantification Peptide identification Spectral library Data-independent acquisition 
ProteomicsFiber type-specific proteomic alterations in R349P desminopathy mice
Desminopathies refer to a group of rare human myopathies and cardiomyopathies, caused by mutations in the desmin gene. So far, there is no causative treatment and little is known about early pathological effects, since alterations in muscle biopsies usually reflect late stages of the disease. Thus, ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD049207 | Pride
Myofibrillar myopathy Desmin Proteomics Fiber types 
ProteomicsBlood contamination in CSF and its impact on quantitative analysis of alpha-synuclein
Analysis of cerebrospinal fluid (CSF) is important for diagnosis of neurological diseases. Specific proteins, which are released from the CNS can be quantitatively monitored. Especially, in the field of neurodegenerative diseases abnormal protein abundance is an important biomarker. However, the qua...
ORGANISM(S): Homo sapiens (Human) 
2020-02-17 | PXD014515 | Pride
Alpha-synuclein Elisa Urine strip Cerebrospinal fluid Bottom-up mass spectrometry Blood contamination Quantification 
ProteomicsThe proteome of neuromelanin granules in dementia with Lewy bodies
Neuromelanin granules (NMGs) are organelle-like structures present in the human substantia nigra pars compacta. Besides neuromelanin, NMGs contain proteins, lipids and metals. As NMG-containing dopaminergic neurons are preferentially lost in Parkinson’s disease and dementia with Lewy bodies (DLB), i...
ORGANISM(S): Homo sapiens (Human) 
2023-02-14 | PXD035310 | Pride
Proteomics Stress granules Substantia nigra pars compacta Dementia with lewy bodies Neurodegeneration Neuromelanin granules 
ProteomicsReproducibility, specificity and accuracy of DIA quantification - DIA analysis
For the complete description see the manuscript. Data dependent acquisition (DDA) is the method of choice for mass spectrometry based proteomics discovery experiments, data-independent acquisition (DIA) is steadily becoming more important. One of the most important requirement to perform a DIA analy...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-08 | PXD012988 | Pride
Dia Label-free quantification Spectral library Data-independent acquisition 
ProteomicsReproducibility, specificity and accuracy of DIA quantification - DDA analysis
Data dependent acquisition (DDA) is the method of choice for mass spectrometry based proteomics discovery experiments, data-independent acquisition (DIA) is steadily becoming more important. One of the most important requirement to perform a DIA analysis is the availability of spectral libraries for...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-08 | PXD012986 | Pride
Data-independent acquisition (dia) Label-free quantification Peptide identification Spectral library 
ProteomicsReproducibility, specificity and accuracy of DIA quantification - OpenSWATH
Data dependent acquisition (DDA) is the method of choice for mass spectrometry based proteomics discovery experiments, data-independent acquisition (DIA) is steadily becoming more important. One of the most important requirement to perform a DIA analysis is the availability of spectral libraries for...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-08 | PXD014956 | Pride
Spike-in C2c12 Dia 
Sort   by:  
 Page size