Sort   by:  
 Page size 
ProteomicsA comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans
DNA damage causes genomic instability underlying many diseases, with traditional analytical approaches providing minimal insight into the spectrum of DNA lesions in vivo. Here we used untargeted chromatography-coupled tandem mass spectrometry-based adductomics (LC-MS/MS) to define the landscape of D...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2023-09-12 | PXD045311 | Pride
Adductomics Strp mrm 
GenomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [ChIP-Seq]
Heart failure is driven by the interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. Coordinate activation of developmental, inflammatory, fibrotic and growth regulators underlies the hallmark phenotypes of pathologic cardiac hypertrophy and contra...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-46668 | biostudies-arrayexpress
UnknownChronobiology of Natriuretic Peptides and Blood Pressure in Lean and Obese Individuals.
Not available
S-EPMC8138944 | biostudies-literature
UnknownRace, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.
Not available
S-EPMC7033629 | biostudies-literature
TranscriptomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [Mouse Heart Expression]
Heart failure (HF) is driven via interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. While pathologic gene transactivation in this context is known to be associated with recruitment of histone acetyl-transferases and local chromatin hyperacetylat...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-48110 | biostudies-arrayexpress
TranscriptomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure [NRVM Expression]
Heart failure (HF) is driven via interplay between master regulatory transcription factors and dynamic alterations in chromatin structure. While pathologic gene transactivation in this context is known to be associated with recruitment of histone acetyl-transferases and local chromatin hyperacetylat...
ORGANISM(S): Rattus norvegicus 
2013-08-06 | E-GEOD-48111 | biostudies-arrayexpress
ProteomicsMultimodality Assessment of HFpEF Skeletal Muscle Reveals Differences in the Machinery of Energy Fuel Metabolism
Aims: Skeletal muscle (SkM) abnormalities may impact exercise capacity in patients with Heart Failure with Preserved Ejection Fraction (HFpEF). We sought to quantify differences in SkM oxidative phosphorylation capacity (OxPhos), fiber composition, and the SkM proteome between HFpEF, hypertensive (H...
ORGANISM(S): Homo sapiens (Human) 
2021-03-30 | PXD025092 | Pride
Exercise Skeletal muscle Hfpef 
TranscriptomicsBET Bromodomains Mediate Transcriptional Pause Release in Heart Failure
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2013-08-06 | E-GEOD-48112 | biostudies-arrayexpress
UnknownMultimodality assessment of heart failure with preserved ejection fraction skeletal muscle reveals differences in the machinery of energy fuel metabolism.
Not available
S-EPMC8318475 | biostudies-literature
UnknownTRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.
Not available
S-EPMC8993766 | biostudies-literature
Sort   by:  
 Page size